Perfluorinated cyclopropyl fused 1,3-oxazin-2-amine compounds as beta-secretase inhibitors and methods of use

PERFLUORINATED CYCLOPROPYL FUSED 1,3-OXAZIN-2-AMINE COMPOUNDS AS BETA-SECRETASE INHIBITORS AND METHODS OF USEOF THE DISCLOSURE The present invention provides a new class of compounds useful for the modulation of beta-secretase enzyme (BACE) activity. The compounds have a general Formula I: {INSERT S...

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Hauptverfasser:	Minatti, Ana Elena, Amegadzie, Albert, Low, Jonathan D, Rumfelt, Shannon, White, Ryan, Guzman-Perez, Angel, Rzasa, Robert M, Brown, James, Sham, Kelvin, Lopez, Patricia, Xue, Qiufen, Smith, Adrian L, Nishimura, Nobuko, Ma, Vu Van, Allen, Jennifer R, Harrington, Paul E, Qian, Wenyuan, Frohn, Michael J
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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