Conjugates for the prevention or treatment of nicotine addiction

Abstract The present invention relates in part to nicotine-derived hapten-carrier conjugates of the formula (111): wherein m, n, W, -(spacer)-, X* and Y are as 5 defined in the description. In certain embodiments, said nicotine-derived hapten carrier conjugates can be used to prepare vaccines for th...

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Hauptverfasser: PRYDE, DAVID CAMERON, STEAD, DAVID ROBERT, MERSON, JAMES RICHARD, MEHELIC, PAUL ROBERT, FINNEMAN, JARI IIMARI, JONES, LYN HOWARD, BHATTACHARYA, KESHAB, GERVAIS, DAVID P, DAVIS, HEATHER LYNN, MCCLUSKIE, MICHAEL JOHN, BROWN, ALAN DANIEL, PARSONS, ERIN KRISTEN, THORN, JENNIFER MARIE, ANASTASIOU, NICKOLAS, KOLHE, PARAG ASHOK
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creator PRYDE, DAVID CAMERON
STEAD, DAVID ROBERT
MERSON, JAMES RICHARD
MEHELIC, PAUL ROBERT
FINNEMAN, JARI IIMARI
JONES, LYN HOWARD
BHATTACHARYA, KESHAB
GERVAIS, DAVID P
DAVIS, HEATHER LYNN
MCCLUSKIE, MICHAEL JOHN
BROWN, ALAN DANIEL
PARSONS, ERIN KRISTEN
THORN, JENNIFER MARIE
ANASTASIOU, NICKOLAS
KOLHE, PARAG ASHOK
description Abstract The present invention relates in part to nicotine-derived hapten-carrier conjugates of the formula (111): wherein m, n, W, -(spacer)-, X* and Y are as 5 defined in the description. In certain embodiments, said nicotine-derived hapten carrier conjugates can be used to prepare vaccines for the treatment and/or prevention of nicotine addiction.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Conjugates for the prevention or treatment of nicotine addiction
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