Inhibitors of carbonic anhydrase IX

Novel radiopharmaceuticals that are useful in diagnostic imaging and therapeutic treatment of disease characterized by over expression of CA-IX comprise a complex that contains a sulfonamide moiety which is capable of binding the active catalytic site of CA- IX, and a radionuclide adapted for radioi...

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Hauptverfasser: LU, GENLIANG, JOYAL, JOHN, BABICH, JOHN W, BARONE, CHRIS, MARESCA, KEVIN P, ZIMMERMAN, CRAIG
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creator LU, GENLIANG
JOYAL, JOHN
BABICH, JOHN W
BARONE, CHRIS
MARESCA, KEVIN P
ZIMMERMAN, CRAIG
description Novel radiopharmaceuticals that are useful in diagnostic imaging and therapeutic treatment of disease characterized by over expression of CA-IX comprise a complex that contains a sulfonamide moiety which is capable of binding the active catalytic site of CA- IX, and a radionuclide adapted for radioimaging and/or radiotherapy:
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Inhibitors of carbonic anhydrase IX
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