Detection of non-nucleic acid analytes using strand displacement exchange reactions

The present invention relates to an analyte detection system for detecting analytes different from DNA and RNA. The system comprises a set of oligonucleotides which may hybridize to each other in specific ways and is able to generate a signal based on the specific hybridization events. The system re...

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Hauptverfasser: KJELSTRUP, MICHAEL BRONDUM, ZHANG, ZHAO, GOTHELF, KURT VESTERAGER, HEJESEN, CHRISTIAN
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention relates to an analyte detection system for detecting analytes different from DNA and RNA. The system comprises a set of oligonucleotides which may hybridize to each other in specific ways and is able to generate a signal based on the specific hybridization events. The system relies on changes in the hybridization equilibrium between the oligonucleotides in the presence of an analyte or analytes, which results in a change in signal.