Substituted cyclopropyl compounds, compositions containing such compounds, and methods of treatment

Substituted cyclopropyl compounds of the formula I: and pharmaceutically acceptable salts thereof are disclosed as useful for treating or preventing type 2 diabetes and similar conditions. The compounds are useful as agonists of the G-protein coupled receptor GPR-119. Pharmaceutical compositions and...

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Hauptverfasser: SUN, WANYING, EDMONDSON, SCOTT D, DAI, XING, WOOD, HAROLD B, MILLER, MICHAEL, MOYES, CHRISTOPHER, DUBOIS, BYRON GABRIEL, LIU, PING, GARFUNKLE, JOIE, BASU, KALLOL, STAMFORD, ANDREW, DEMONG, DUANE, HU, ZHIYONG
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creator SUN, WANYING
EDMONDSON, SCOTT D
DAI, XING
WOOD, HAROLD B
MILLER, MICHAEL
MOYES, CHRISTOPHER
DUBOIS, BYRON GABRIEL
LIU, PING
GARFUNKLE, JOIE
BASU, KALLOL
STAMFORD, ANDREW
DEMONG, DUANE
HU, ZHIYONG
description Substituted cyclopropyl compounds of the formula I: and pharmaceutically acceptable salts thereof are disclosed as useful for treating or preventing type 2 diabetes and similar conditions. The compounds are useful as agonists of the G-protein coupled receptor GPR-119. Pharmaceutical compositions and methods of treatment are also included.
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subjects AGRICULTURE
ANIMAL HUSBANDRY
BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES
FISHING
FORESTRY
HUMAN NECESSITIES
HUNTING
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PEST REPELLANTS OR ATTRACTANTS
PLANT GROWTH REGULATORS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF
TRAPPING
title Substituted cyclopropyl compounds, compositions containing such compounds, and methods of treatment
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