Benzenesulfonamide derivatives
The present invention relates to a benzenesulfonamide derivative of formula (I), which. is useful as an active ingredient of pharmaceutical preparations. The benzenesulfonamide derivatives of the present invention have CCR3 (CC type chemokine receptor) antagonistic activity, and can be used for the...
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| creator | MORIWAKI, TOSHIYA MARUMO, MAKIKO FUKUSHIMA, KEIKO YOSHIDA, NAGAHIRO BACON, KEVIN URBAHNS, KLAUS TSUNO, NAOKI NUNAMI, NORIKO LI, YINGFU SUGIMOTO, HIROMI HASHIMOTO, KENTARO |
| description | The present invention relates to a benzenesulfonamide derivative of formula (I), which. is useful as an active ingredient of pharmaceutical preparations. The benzenesulfonamide derivatives of the present invention have CCR3 (CC type chemokine receptor) antagonistic activity, and can be used for the prophylaxis and treatment of diseases associated with CCR3 activity, in particular for the treatment of asthma, atopic dermatitis, allergic rhinitis and other inflammatory/immunological disorders. In said formula, X represents 0 or S; R4 represents formulae (a), (b), (c), (d), (e), (f), (g;), (h), (i) or (j), the other substituents are as defined in claim |
| format | Patent |
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The benzenesulfonamide derivatives of the present invention have CCR3 (CC type chemokine receptor) antagonistic activity, and can be used for the prophylaxis and treatment of diseases associated with CCR3 activity, in particular for the treatment of asthma, atopic dermatitis, allergic rhinitis and other inflammatory/immunological disorders. 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The benzenesulfonamide derivatives of the present invention have CCR3 (CC type chemokine receptor) antagonistic activity, and can be used for the prophylaxis and treatment of diseases associated with CCR3 activity, in particular for the treatment of asthma, atopic dermatitis, allergic rhinitis and other inflammatory/immunological disorders. In said formula, X represents 0 or S; R4 represents formulae (a), (b), (c), (d), (e), (f), (g;), (h), (i) or (j), the other substituents are as defined in claim</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| title | Benzenesulfonamide derivatives |
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