Conjugates for the prevention or treatment of nicotine addiction

The present invention relates in part to nicotine-derived hapten-carrier conjugates of the formula (III): wherein m, n, W, -(spacer)-, X* and Y are as defined in the description. In certain embodiments, said nicotine-derived hapten-carrier conjugates can be used to prepare vaccines for the treatment...

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Bibliographische Detailangaben
Hauptverfasser:	PRYDE, DAVID CAMERON, STEAD, DAVID ROBERT, MERSON, JAMES RICHARD, MEHELIC, PAUL ROBERT, JONES, LYN HOWARD, BHATTACHARYA, KESHAB, GERVAIS, DAVID P, FINNEMAN, JARI ILMARI, DAVIS, HEATHER LYNN, MCCLUSKIE, MICHAEL JOHN, BROWN, ALAN DANIEL, PARSONS, ERIN KRISTEN, THORN, JENNIFER MARIE, ANASTASIOU, NICKOLAS, KOLHE, PARAG ASHOK
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates in part to nicotine-derived hapten-carrier conjugates of the formula (III): wherein m, n, W, -(spacer)-, X* and Y are as defined in the description. In certain embodiments, said nicotine-derived hapten-carrier conjugates can be used to prepare vaccines for the treatment and/or prevention of nicotine addiction.