Anaplastic lymphoma kinase modulators and methods of use
Abstract The present invention comprises compounds and pharmaceutical compositions comprising the compounds that are inhibitors of ALK. The invention also comprises methods of using the compounds and compositions to treat diseases mediated by ALK, including diseases such as cancer, immunological dis...
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creator | MANALO, JEAN-CLAIRE L BUSSENIUS, JOERG KENNEDY, ABIGAIL R PETO, CSABA J DUBENKO, LARISA KHOURY, RICHARD G CURTIS, JEFFRY KIMO BLAZEY, CHARLES M COSTANZO, SIMONA KIM, ANGIE I BOWLES, OWEN JOSEPH ANAND, NEEL KUMAR RICE, KENNETH D TSANG, TSZE H |
description | Abstract The present invention comprises compounds and pharmaceutical compositions comprising the compounds that are inhibitors of ALK. The invention also comprises methods of using the compounds and compositions to treat diseases mediated by ALK, including diseases such as cancer, immunological disorders, cardiovascular diseases, and other degenerative disorders. |
format | Patent |
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subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
title | Anaplastic lymphoma kinase modulators and methods of use |
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