Method for the differentiation of human adult stem cells into insulin-secreting cells

Method for the differentiation of human adult stem cells into insulin-secreting cells

Disclosed is a method for differentiating human adult stem cells into insulin-secreting cells. Human adult stem 5 cells, isolated from the subcutaneous adipose tissues around the eyes, are induced to differentiate into insulin-secreting cells in a medium in the presence of cytokines and growth facto...

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Hauptverfasser: KANG, HYUN MI, KIM, HAE KWON
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BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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KIM, HAE KWON
description Disclosed is a method for differentiating human adult stem cells into insulin-secreting cells. Human adult stem 5 cells, isolated from the subcutaneous adipose tissues around the eyes, are induced to differentiate into insulin-secreting cells in a medium in the presence of cytokines and growth factors including B27 supplement, fibroblast growth factor-2, epidermal growth factor, 10 nicotinamide, glucagon-like peptide-1, activin A, insulin like growth factor, betacellulin, etc., with a glucose shift from a high concentration to a low concentration. Having the ability to producing insulin and C-peptide at high levels, the insulin-secreting cells can be excellent 15 curatives for type 1 diabetes mellitus.
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
title Method for the differentiation of human adult stem cells into insulin-secreting cells
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