Process for the preparation of vorinostat

Process for the preparation of vorinostat

The present invention relates to an improved process for the preparation of the active pharmaceutical ingredient vorinostat. In particular it relates to a process for preparing vorinostat substantially free from impurities, involving suberic acid, aniline and hydroxylamine as starting materials.

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Hauptverfasser: MADHUKAR S. PATIL, SANDEEP G. MEKDE, HEMANT M. MANDE, RAHUL A. BHALERAO, VINAYAK G. GORE
Format: Patent
Sprache:eng
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
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creator MADHUKAR S. PATIL
SANDEEP G. MEKDE
HEMANT M. MANDE
RAHUL A. BHALERAO
VINAYAK G. GORE
description The present invention relates to an improved process for the preparation of the active pharmaceutical ingredient vorinostat. In particular it relates to a process for preparing vorinostat substantially free from impurities, involving suberic acid, aniline and hydroxylamine as starting materials.
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subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
title Process for the preparation of vorinostat
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