Pharmaceutical composition utilising combinations of variants of the gonadotropin-liberating hormone (GnRH) as immunogen
A pharmaceutical composition using natural gonadotropin - releasing hormone (GnRH), and/or some of its mimetic peptides, indistinctly bound by its amino or carboxyl extremes to a carrier molecule; in one case by its carboxyl extreme and in the other case by the amino terminal extreme, thus eliciting...
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| creator | EULOGIO PIMENTEL VAZQUEZ YOVISLEIDYS LOPEZ SAEZ NIURKA ONEYSI ARTEAGA MORE ROBERTO BASULTO BAKER MARIA CASTRO SANTANA OSVALDO REYES ACOSTA LESVIA CALZADA AGUILERA JESUS ARTURO JUNCO BARRANCO EDDY EMILIO BOVER FUENTES FRANKLIN FUENTES AGUILAR GERARDO ENRIQUE GUILLEN NIETO LUIS ALBERTO AGUERO BARROCAL HILDA ELISA GARAY PEREZ |
| description | A pharmaceutical composition using natural gonadotropin - releasing hormone (GnRH), and/or some of its mimetic peptides, indistinctly bound by its amino or carboxyl extremes to a carrier molecule; in one case by its carboxyl extreme and in the other case by the amino terminal extreme, thus eliciting a faster and more potent immunological response against the endogenous GnRH hormone. This finally leads to the ablation of the GnRH and consequently of the rest of the involved hormones in the stream GnRH/LH-FSH/Testosterone-(estrogens). An advantage of this formulation consists on facilitating the exposition to the immune system of a greater number of epitopes of the GnRH or its mimetics, minimizing thus the steric hindrance produced by the carriers. This invention has a direct application in the castration of pets and animals of economic interest, in the control of human fertility as well as in the treatment of hormone-sensitive tumors, such as that of the prostate, the breast, ovary, the endometry, testicles, hypophysis, salivary glands and other kinds of human tumors. |
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This finally leads to the ablation of the GnRH and consequently of the rest of the involved hormones in the stream GnRH/LH-FSH/Testosterone-(estrogens). An advantage of this formulation consists on facilitating the exposition to the immune system of a greater number of epitopes of the GnRH or its mimetics, minimizing thus the steric hindrance produced by the carriers. This invention has a direct application in the castration of pets and animals of economic interest, in the control of human fertility as well as in the treatment of hormone-sensitive tumors, such as that of the prostate, the breast, ovary, the endometry, testicles, hypophysis, salivary glands and other kinds of human tumors.</description><language>eng</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2011</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20110609&DB=EPODOC&CC=AU&NR=2009298305A8$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25544,76293</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20110609&DB=EPODOC&CC=AU&NR=2009298305A8$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>EULOGIO PIMENTEL VAZQUEZ</creatorcontrib><creatorcontrib>YOVISLEIDYS LOPEZ SAEZ</creatorcontrib><creatorcontrib>NIURKA ONEYSI ARTEAGA MORE</creatorcontrib><creatorcontrib>ROBERTO BASULTO BAKER</creatorcontrib><creatorcontrib>MARIA CASTRO SANTANA</creatorcontrib><creatorcontrib>OSVALDO REYES ACOSTA</creatorcontrib><creatorcontrib>LESVIA CALZADA AGUILERA</creatorcontrib><creatorcontrib>JESUS ARTURO JUNCO BARRANCO</creatorcontrib><creatorcontrib>EDDY EMILIO BOVER FUENTES</creatorcontrib><creatorcontrib>FRANKLIN FUENTES AGUILAR</creatorcontrib><creatorcontrib>GERARDO ENRIQUE GUILLEN NIETO</creatorcontrib><creatorcontrib>LUIS ALBERTO AGUERO BARROCAL</creatorcontrib><creatorcontrib>HILDA ELISA GARAY PEREZ</creatorcontrib><title>Pharmaceutical composition utilising combinations of variants of the gonadotropin-liberating hormone (GnRH) as immunogen</title><description>A pharmaceutical composition using natural gonadotropin - releasing hormone (GnRH), and/or some of its mimetic peptides, indistinctly bound by its amino or carboxyl extremes to a carrier molecule; in one case by its carboxyl extreme and in the other case by the amino terminal extreme, thus eliciting a faster and more potent immunological response against the endogenous GnRH hormone. This finally leads to the ablation of the GnRH and consequently of the rest of the involved hormones in the stream GnRH/LH-FSH/Testosterone-(estrogens). An advantage of this formulation consists on facilitating the exposition to the immune system of a greater number of epitopes of the GnRH or its mimetics, minimizing thus the steric hindrance produced by the carriers. This invention has a direct application in the castration of pets and animals of economic interest, in the control of human fertility as well as in the treatment of hormone-sensitive tumors, such as that of the prostate, the breast, ovary, the endometry, testicles, hypophysis, salivary glands and other kinds of human tumors.</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2011</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjsEKgkAURd20iOofBtrUQhAl0KVE5TKi1vK0pz6YeU9mxujzG6MPaHUvh3PhLqP3dQBroMXJUwtatWJGceRJWAWkyRH3M22IYaZOSadeYAnYf7sfUPXC8BRvZSSONTVogxt2g1gjjGp34Vu1V-AUGTOx9MjraNGBdrj55Srank_3YxXjKDW6MVxi9HX5SJOkSIs8Sw5lnv1nfQB6J0fu</recordid><startdate>20110609</startdate><enddate>20110609</enddate><creator>EULOGIO PIMENTEL VAZQUEZ</creator><creator>YOVISLEIDYS LOPEZ SAEZ</creator><creator>NIURKA ONEYSI ARTEAGA MORE</creator><creator>ROBERTO BASULTO BAKER</creator><creator>MARIA CASTRO SANTANA</creator><creator>OSVALDO REYES ACOSTA</creator><creator>LESVIA CALZADA AGUILERA</creator><creator>JESUS ARTURO JUNCO BARRANCO</creator><creator>EDDY EMILIO BOVER FUENTES</creator><creator>FRANKLIN FUENTES AGUILAR</creator><creator>GERARDO ENRIQUE GUILLEN NIETO</creator><creator>LUIS ALBERTO AGUERO BARROCAL</creator><creator>HILDA ELISA GARAY PEREZ</creator><scope>EVB</scope></search><sort><creationdate>20110609</creationdate><title>Pharmaceutical composition utilising combinations of variants of the gonadotropin-liberating hormone (GnRH) as immunogen</title><author>EULOGIO PIMENTEL VAZQUEZ ; YOVISLEIDYS LOPEZ SAEZ ; NIURKA ONEYSI ARTEAGA MORE ; ROBERTO BASULTO BAKER ; MARIA CASTRO SANTANA ; OSVALDO REYES ACOSTA ; LESVIA CALZADA AGUILERA ; JESUS ARTURO JUNCO BARRANCO ; EDDY EMILIO BOVER FUENTES ; FRANKLIN FUENTES AGUILAR ; GERARDO ENRIQUE GUILLEN NIETO ; LUIS ALBERTO AGUERO BARROCAL ; HILDA ELISA GARAY PEREZ</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_AU2009298305A83</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2011</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>EULOGIO PIMENTEL VAZQUEZ</creatorcontrib><creatorcontrib>YOVISLEIDYS LOPEZ SAEZ</creatorcontrib><creatorcontrib>NIURKA ONEYSI ARTEAGA MORE</creatorcontrib><creatorcontrib>ROBERTO BASULTO BAKER</creatorcontrib><creatorcontrib>MARIA CASTRO SANTANA</creatorcontrib><creatorcontrib>OSVALDO REYES ACOSTA</creatorcontrib><creatorcontrib>LESVIA CALZADA AGUILERA</creatorcontrib><creatorcontrib>JESUS ARTURO JUNCO BARRANCO</creatorcontrib><creatorcontrib>EDDY EMILIO BOVER FUENTES</creatorcontrib><creatorcontrib>FRANKLIN FUENTES AGUILAR</creatorcontrib><creatorcontrib>GERARDO ENRIQUE GUILLEN NIETO</creatorcontrib><creatorcontrib>LUIS ALBERTO AGUERO BARROCAL</creatorcontrib><creatorcontrib>HILDA ELISA GARAY PEREZ</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>EULOGIO PIMENTEL VAZQUEZ</au><au>YOVISLEIDYS LOPEZ SAEZ</au><au>NIURKA ONEYSI ARTEAGA MORE</au><au>ROBERTO BASULTO BAKER</au><au>MARIA CASTRO SANTANA</au><au>OSVALDO REYES ACOSTA</au><au>LESVIA CALZADA AGUILERA</au><au>JESUS ARTURO JUNCO BARRANCO</au><au>EDDY EMILIO BOVER FUENTES</au><au>FRANKLIN FUENTES AGUILAR</au><au>GERARDO ENRIQUE GUILLEN NIETO</au><au>LUIS ALBERTO AGUERO BARROCAL</au><au>HILDA ELISA GARAY PEREZ</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Pharmaceutical composition utilising combinations of variants of the gonadotropin-liberating hormone (GnRH) as immunogen</title><date>2011-06-09</date><risdate>2011</risdate><abstract>A pharmaceutical composition using natural gonadotropin - releasing hormone (GnRH), and/or some of its mimetic peptides, indistinctly bound by its amino or carboxyl extremes to a carrier molecule; in one case by its carboxyl extreme and in the other case by the amino terminal extreme, thus eliciting a faster and more potent immunological response against the endogenous GnRH hormone. This finally leads to the ablation of the GnRH and consequently of the rest of the involved hormones in the stream GnRH/LH-FSH/Testosterone-(estrogens). An advantage of this formulation consists on facilitating the exposition to the immune system of a greater number of epitopes of the GnRH or its mimetics, minimizing thus the steric hindrance produced by the carriers. This invention has a direct application in the castration of pets and animals of economic interest, in the control of human fertility as well as in the treatment of hormone-sensitive tumors, such as that of the prostate, the breast, ovary, the endometry, testicles, hypophysis, salivary glands and other kinds of human tumors.</abstract><oa>free_for_read</oa></addata></record> |
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| title | Pharmaceutical composition utilising combinations of variants of the gonadotropin-liberating hormone (GnRH) as immunogen |
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