Methods for determining sodium-proton-exchanger ligand efficiency

The present invention relates to methods for determining the efficiency of an ion channel ligand comprising (a) contacting a cell expressing the ion channel with (i) plasma of an animal and (ii) the ion channel ligand and (b) determining the effect of the ion channel ligand on the cell.

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Bibliographische Detailangaben
Hauptverfasser: HANS-WILLI JANSEN, STEFAN SCHAEFER, URSULA SCHINDLER, THOMAS LICHER
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention relates to methods for determining the efficiency of an ion channel ligand comprising (a) contacting a cell expressing the ion channel with (i) plasma of an animal and (ii) the ion channel ligand and (b) determining the effect of the ion channel ligand on the cell.