Nonimmunosuppressive cyclosporine analogue molecules

The compounds of the present invention are non-immunosupressive cyclosporine analogue molecules that are able to bind cyclophilin. Said compounds include a modified side chain of amino acid I of cyclosporin A, consisting of an oxyalkyl having substituents R', R1 and R2, where R' is H or Ac...

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Bibliographische Detailangaben
Hauptverfasser: DAN J. TREPANIER, BRUCE W. FENSKE, DARREN R. URE, DAVE MCGLADE, ALEXANDER HEGMANS, MARK D. ABEL, SHIN SUGIYAMA, DAVID P. CZAJKOWSKI
Format: Patent
Sprache:eng
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