Compounds that are ERK inhibitors

Disclosed are the ERK inhibitors of formula 1.0: and the pharmaceutically acceptable salts, and solvates thereof. Q is a tetrahydopyridinyl ring. All other substitutents are as defined herein. Also disclosed are methods of treating cancer using the compounds of formula 1.0.

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Bibliographische Detailangaben
Hauptverfasser:	TSUI, HONUNG, COOPER, ALAN B, SAMATAR, AHMED A, GUDIPATI, SUBRAHMANYAM, SHIH, NENG-YANG, GAO, XIAOLEI, ZHU, LIANG, SHIPPS JR., GERALD A. JR, YAO, XIN, BOGA, SOBHANA BABU, NAN, YANG, KELLY, JOSEPH M, ZHU, HUGH Y, PATEL, MEHUL F, DESAI, JAGDISH A, DENG, YONGQI, ALHASSAN, ABDUL-BASIT, PALIWAL, SUNIL, DOLL, RONALD J, WANG, JAMES J-S
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	Disclosed are the ERK inhibitors of formula 1.0: and the pharmaceutically acceptable salts, and solvates thereof. Q is a tetrahydopyridinyl ring. All other substitutents are as defined herein. Also disclosed are methods of treating cancer using the compounds of formula 1.0.