Non-aggregating virus formulation

The present invention is a composition comprising a virus, a polyol and a zwitteronic compound. The present invention is also an assay for viral aggregation, which comprises analysing the size of the viral particles in a sample, wherein the particles are in admixture with a polyol, and determining f...

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Bibliographische Detailangaben
Hauptverfasser: SEPPO YLA-HERTTUALA, MINNA NOKELAINEN, ROBERT SHAW, TUOMAS MANTYLA
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention is a composition comprising a virus, a polyol and a zwitteronic compound. The present invention is also an assay for viral aggregation, which comprises analysing the size of the viral particles in a sample, wherein the particles are in admixture with a polyol, and determining from the size whether the sample contains substantially only acceptable, non-aggregated particles.