Quinolinone derivatives as PARP and TANK inhibitors

The present invention provides compounds of Formula (I), their use as PARP inhibitors as well as pharmaceutical compositions comprising said compounds, wherein R, R, R, R, R, R, R, n, m and X have defined meanings.

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Bibliographische Detailangaben
Hauptverfasser: FREYNE, EDDY JEAN EDGARD, PILATTE, ISABELLE NOELLE CONSTANCE, VIALARD, JORGE EDUARDO, PONCELET, VIRGINIE SOPHIE, ROUX, BRUNO, MEYER, CHRISTOPHE, MEVELLEC, LAURENCE ANNE, MARCONNET-DECRANE, LAURENCE FRANCOISE BERNADETTE, ADELINET, CHRISTOPHE DENIS, MACRITCHIE, JACQUELINE ANNE, BOURDREZ, XAVIER MARC, OWENS, ANDREW PATE, STORCK, PIERRE-HENRI, DUFFY, JAMES EDWARD STEWART, ANGIBAUD, PATRICK RENE, PASQUIER, ELISABETH THERESE JEANNE
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention provides compounds of Formula (I), their use as PARP inhibitors as well as pharmaceutical compositions comprising said compounds, wherein R, R, R, R, R, R, R, n, m and X have defined meanings.