Tricyclic amine derivatives as protein tyrosine kinase inhibitors
The invention relates to new bicyclic heterocyclic derivative compounds of Formula (I), to pharmaceutical compositions comprising said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer. The compounds of Formula (I) are inhibitors of FGFR, VEGFR or PDGFR.
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| creator | NIJJAR, RAJDEEP KAUR GILL, ADRIAN LIAM VICKERSTAFFE, EMMA TAYLOR, RICHARD DAVID BESONG, GILBERT EBAI MURRAY, CHRISTOPHER WILLIAM CALLAGHAN, OWEN SAXTY, GORDON BERDINI, VALERIO O'BRIEN, MICHAEL ALISTAIR CONGREVE, MILES STUART PIKE, ANDREW CARR, MARIA GRAZIA GRIFFITHS-JONES, CHARLOTTE MARY MADIN, ANDREW |
| description | The invention relates to new bicyclic heterocyclic derivative compounds of Formula (I), to pharmaceutical compositions comprising said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer. The compounds of Formula (I) are inhibitors of FGFR, VEGFR or PDGFR. |
| format | Patent |
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The compounds of Formula (I) are inhibitors of FGFR, VEGFR or PDGFR.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Tricyclic amine derivatives as protein tyrosine kinase inhibitors |
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