Quinazolines for PDK1 inhibition
The invention provides novel compounds that are inhibitors of PDK1. Also provided are pharmaceutical compositions including the compounds, and methods of treating proliferative diseases, such as cancers, with the compounds or compositions.
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| creator | MINA AIKAWA JEREMY M. MURRAY SHARADA SUBRAMANIAN XIAOJING M. WANG JEFFREY DOVE XIAODONG LIN YASHEEN ZHOU SAVITHRI RAMURTHY ROBERT L. WARNE STEVEN E. BASHAM WEI SHU PAYMAN AMIRI ALICE C. RICO RAMA JAIN |
| description | The invention provides novel compounds that are inhibitors of PDK1. Also provided are pharmaceutical compositions including the compounds, and methods of treating proliferative diseases, such as cancers, with the compounds or compositions. |
| format | Patent |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Quinazolines for PDK1 inhibition |
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