Estratriene derivatives and their uses as 17beta-hydr0xyster0id dehydrogenase inhibitors

Estratriene derivatives and their uses as 17beta-hydr0xyster0id dehydrogenase inhibitors

This invention relates to novel estratrien-triazoles of general formula (I) useful in therapy, especially for use in the treatment and/or prevention of a steroid hormone dependent disorder, preferably a steroid hormone dependent disease or disorder requiring the inhibition of a 17 -hydroxysteroid de...

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Hauptverfasser: KOSKIMIES, PASI, THOLE, HEINRICH-HUBERT, MESSINGER, JOSEF, KALLIO, LILA, HUSEN, BETTINA, SCHOEN, UWE
Format: Patent
Sprache:eng
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CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
STEROIDS
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creator KOSKIMIES, PASI
THOLE, HEINRICH-HUBERT
MESSINGER, JOSEF
KALLIO, LILA
HUSEN, BETTINA
SCHOEN, UWE
description This invention relates to novel estratrien-triazoles of general formula (I) useful in therapy, especially for use in the treatment and/or prevention of a steroid hormone dependent disorder, preferably a steroid hormone dependent disease or disorder requiring the inhibition of a 17 -hydroxysteroid dehydrogenase (17 -HSD) such as 17 -HSD type 1, type 2 or type 3 enzyme.
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subjects CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
STEROIDS
title Estratriene derivatives and their uses as 17beta-hydr0xyster0id dehydrogenase inhibitors
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