Estratriene derivatives and their uses as 17beta-hydr0xyster0id dehydrogenase inhibitors

This invention relates to novel estratrien-triazoles of general formula (I) useful in therapy, especially for use in the treatment and/or prevention of a steroid hormone dependent disorder, preferably a steroid hormone dependent disease or disorder requiring the inhibition of a 17 -hydroxysteroid de...

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Hauptverfasser: KOSKIMIES, PASI, THOLE, HEINRICH-HUBERT, MESSINGER, JOSEF, KALLIO, LILA, HUSEN, BETTINA, SCHOEN, UWE
Format: Patent
Sprache:eng
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Zusammenfassung:This invention relates to novel estratrien-triazoles of general formula (I) useful in therapy, especially for use in the treatment and/or prevention of a steroid hormone dependent disorder, preferably a steroid hormone dependent disease or disorder requiring the inhibition of a 17 -hydroxysteroid dehydrogenase (17 -HSD) such as 17 -HSD type 1, type 2 or type 3 enzyme.