Pyrazole compounds and uses thereof

The present invention is directed to compounds of the formula:and pharmaceutically acceptable salts thereof, to pharmaceutical compositions comprising same, and to methods for inhibiting protein prenylation in an organism using the same, where R1, R2, R3, R4, R5, R6, R7 and X are defined herein.

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Hauptverfasser: JANNA C PURDY, ZITA LATONA, BRADLEY B BROWN, SARAH TAVARES, PATRICK J CASEY
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creator JANNA C PURDY
ZITA LATONA
BRADLEY B BROWN
SARAH TAVARES
PATRICK J CASEY
description The present invention is directed to compounds of the formula:and pharmaceutically acceptable salts thereof, to pharmaceutical compositions comprising same, and to methods for inhibiting protein prenylation in an organism using the same, where R1, R2, R3, R4, R5, R6, R7 and X are defined herein.
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HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2004</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20040722&amp;DB=EPODOC&amp;CC=AU&amp;NR=2004202912A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76289</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20040722&amp;DB=EPODOC&amp;CC=AU&amp;NR=2004202912A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>JANNA C PURDY</creatorcontrib><creatorcontrib>ZITA LATONA</creatorcontrib><creatorcontrib>BRADLEY B BROWN</creatorcontrib><creatorcontrib>SARAH TAVARES</creatorcontrib><creatorcontrib>PATRICK J CASEY</creatorcontrib><title>Pyrazole compounds and uses thereof</title><description>The present invention is directed to compounds of the formula:and pharmaceutically acceptable salts thereof, to pharmaceutical compositions comprising same, and to methods for inhibiting protein prenylation in an organism using the same, where R1, R2, R3, R4, R5, R6, R7 and X are defined herein.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2004</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZFAOqCxKrMrPSVVIzs8tyC_NSylWSMxLUSgtTi1WKMlILUrNT-NhYE1LzClO5YXS3AzKbq4hzh66qQX58anFBYnJqXmpJfGOoUYGBiZGBkaWhkaOhsbEqQIAjKYnVA</recordid><startdate>20040722</startdate><enddate>20040722</enddate><creator>JANNA C PURDY</creator><creator>ZITA LATONA</creator><creator>BRADLEY B BROWN</creator><creator>SARAH TAVARES</creator><creator>PATRICK J CASEY</creator><scope>EVB</scope></search><sort><creationdate>20040722</creationdate><title>Pyrazole compounds and uses thereof</title><author>JANNA C PURDY ; 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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Pyrazole compounds and uses thereof
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