PYRAZOLE COMPOUNDS AS INTEGRIN RECEPTOR ANTAGONISTS DERIVATIVES
The present invention relates to a class of compounds represented by the Formula I or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising compounds of the Formula I, and methods of selectively inhibiting or antagonizing the alphaVbeta3 and/or the alphaVbeta5 integrin w...
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creator | ALBERT KHILEVICH YAPING WANG MARK, L. BOYS PREETE GANDHI MARK RUSSELL RENEE, M. HUFF VICTORIA DOWNS THOMAS, D. PENNING DALE, P. SPANGLER BARBARA, B. CHEN |
description | The present invention relates to a class of compounds represented by the Formula I or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising compounds of the Formula I, and methods of selectively inhibiting or antagonizing the alphaVbeta3 and/or the alphaVbeta5 integrin without significantly inhibiting the alphaVbeta6 integrin. |
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BOYS ; PREETE GANDHI ; MARK RUSSELL ; RENEE, M. HUFF ; VICTORIA DOWNS ; THOMAS, D. PENNING ; DALE, P. SPANGLER ; BARBARA, B. CHEN</creatorcontrib><description>The present invention relates to a class of compounds represented by the Formula I or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising compounds of the Formula I, and methods of selectively inhibiting or antagonizing the alphaVbeta3 and/or the alphaVbeta5 integrin without significantly inhibiting the alphaVbeta6 integrin.</description><edition>7</edition><language>eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>2004</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20040722&DB=EPODOC&CC=AU&NR=2003297409A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20040722&DB=EPODOC&CC=AU&NR=2003297409A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>ALBERT KHILEVICH</creatorcontrib><creatorcontrib>YAPING WANG</creatorcontrib><creatorcontrib>MARK, L. 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CHEN</creatorcontrib><title>PYRAZOLE COMPOUNDS AS INTEGRIN RECEPTOR ANTAGONISTS DERIVATIVES</title><description>The present invention relates to a class of compounds represented by the Formula I or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising compounds of the Formula I, and methods of selectively inhibiting or antagonizing the alphaVbeta3 and/or the alphaVbeta5 integrin without significantly inhibiting the alphaVbeta6 integrin.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2004</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZLAPiAxyjPL3cVVw9vcN8A_1cwlWcAxW8PQLcXUP8vRTCHJ1dg0I8Q9ScPQLcXT39_MMDglWcHEN8gxzDPEMcw3mYWBNS8wpTuWF0twMym6uIc4euqkF-fGpxQWJyal5qSXxjqFGBgbGRpbmJgaWjobGxKkCAHMqK9U</recordid><startdate>20040722</startdate><enddate>20040722</enddate><creator>ALBERT KHILEVICH</creator><creator>YAPING WANG</creator><creator>MARK, L. 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SPANGLER</creatorcontrib><creatorcontrib>BARBARA, B. CHEN</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>ALBERT KHILEVICH</au><au>YAPING WANG</au><au>MARK, L. BOYS</au><au>PREETE GANDHI</au><au>MARK RUSSELL</au><au>RENEE, M. HUFF</au><au>VICTORIA DOWNS</au><au>THOMAS, D. PENNING</au><au>DALE, P. SPANGLER</au><au>BARBARA, B. CHEN</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>PYRAZOLE COMPOUNDS AS INTEGRIN RECEPTOR ANTAGONISTS DERIVATIVES</title><date>2004-07-22</date><risdate>2004</risdate><abstract>The present invention relates to a class of compounds represented by the Formula I or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising compounds of the Formula I, and methods of selectively inhibiting or antagonizing the alphaVbeta3 and/or the alphaVbeta5 integrin without significantly inhibiting the alphaVbeta6 integrin.</abstract><edition>7</edition><oa>free_for_read</oa></addata></record> |
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subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
title | PYRAZOLE COMPOUNDS AS INTEGRIN RECEPTOR ANTAGONISTS DERIVATIVES |
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