Phosphodiesterase 4 inhibitors, including N-substituted aniline and diphenylamine analogs

PDE4 inhibition is achieved by novel compounds, e.g., N-substituted aniline and diphenylamine analogs. The compounds of the present invention are of Formula I: wherein R1, R2, R3 and R4 are as defined herein.

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Hauptverfasser: HANS-JURGEN ERNST HESS, AXEL UNTERBECK, ROBERT F. DUNN, WILLIAM FREDERICK JR. BRUBAKER, ASHOK TEHIM, RICHARD A. SCHUMACHER, ALLEN T. HOPPER, ERIK KUESTER
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creator HANS-JURGEN ERNST HESS
AXEL UNTERBECK
ROBERT F. DUNN
WILLIAM FREDERICK JR. BRUBAKER
ASHOK TEHIM
RICHARD A. SCHUMACHER
ALLEN T. HOPPER
ERIK KUESTER
description PDE4 inhibition is achieved by novel compounds, e.g., N-substituted aniline and diphenylamine analogs. The compounds of the present invention are of Formula I: wherein R1, R2, R3 and R4 are as defined herein.
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subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Phosphodiesterase 4 inhibitors, including N-substituted aniline and diphenylamine analogs
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