Use of a pharmaceutical composition containing Epidermal Growth Factor (EGF) for diabetic foot amputation prevention
Use of epidermal growth factor (EGF) in a composition for treating a lesion, ischemic or caused by reperfusion, in a diabetic patient, by local infiltration into the tissues that form the borders and base of the lesion, is new. An independent claim is also included for a pharmaceutical composition (...
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| creator | NEOBALIS FRANCO PEREZ JORGE SOTOLONGO PENA CALIXTO VALDES PEREZ LARISSA CHACON CORVEA GERARDO E GUILLEN NIETO JOSE I. FERNANDEZ MONTEQUIN HAYDEE GERONIMO PEREZ LEONARDO CANAN-HADEN FRIAS HECTOR SANTANA MILIAN LUIS HERRERA MARTINEZ INGRID ROJAS CONSTANTIN JOSE FERNANDEZ MONTEQUIN JORGE BERLANGA ACOSTA GERARDO E. GUILLEN NIETO |
| description | Use of epidermal growth factor (EGF) in a composition for treating a lesion, ischemic or caused by reperfusion, in a diabetic patient, by local infiltration into the tissues that form the borders and base of the lesion, is new. An independent claim is also included for a pharmaceutical composition (liquid or freeze-dried) for treating the specified lesions that contains 10-1000 Microg/ml of EGF combined with at least one of fibronectin; raffinose; poly(ethyleneimine); an isoflavonoid (e.g. rutin); lidocaine; adenosine or guanosine triphosphates, or their salts; nicotinamide; L-Arg or heparin salt. ACTIVITY : Antidiabetic; Vulnerary. MECHANISM OF ACTION : Stimulation of cell proliferation. |
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An independent claim is also included for a pharmaceutical composition (liquid or freeze-dried) for treating the specified lesions that contains 10-1000 Microg/ml of EGF combined with at least one of fibronectin; raffinose; poly(ethyleneimine); an isoflavonoid (e.g. rutin); lidocaine; adenosine or guanosine triphosphates, or their salts; nicotinamide; L-Arg or heparin salt. ACTIVITY : Antidiabetic; Vulnerary. MECHANISM OF ACTION : Stimulation of cell proliferation.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Use of a pharmaceutical composition containing Epidermal Growth Factor (EGF) for diabetic foot amputation prevention |
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