Preparation of flumethasone and its 17-carboxyl androsten analogue

A process for the preparation of high purity flumethasone in high yield involves C3 protecting 9,11beta-epoxy-17alpha,21-dihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione,21-acetate, fluorinating at 6alpha, removing the C3 protecting group, fluorinating the 9,11-epoxy group. The resulting flumetha...

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Bibliographische Detailangaben

Hauptverfasser:	ZITA MENDES, IVAN VILLAX
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY METALLURGY ORGANIC CHEMISTRY STEROIDS
Online-Zugang:	Volltext bestellen
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