Dialdehydes as immunostimulatory adjuvants and cross-linkers for producing immunogenic preparations and generating pressure and cross-linked treated cells for enhancing and augmenting the immune response against cancers, tumors and pathogenic diseases
The invention describes a method of preincubating cells with dialdehydes, preferably a 2',3'-nucleoside or nucleotide dialdehyde as cross-linkers, prior to modifying the cell membrane components of the preincubated cells by exposure to hydrostatic pressure to produce potent immunogenic pre...
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