Anti-picornaviral ligands via a combinatorial computational and synthetic approach

The present invention provides structure-based combinatorial libraries of compounds containing the functional group minima of picornaviruses including poliovirus and rhinovirus. The libraries can be used to screen for therapeutical antiviral compounds, e.g., anti-picornaviral capsid-binding compound...

Ausführliche Beschreibung

Bibliographische Detailangaben

Hauptverfasser:	JAMES M. HOGLE, JAMES LI-WEN CHEH, LYLE D. ISAACS, GEORGE M. WHITESIDES, DIANE M. JOSEPH-MCCARTHY, MARTIN KARPLUS
Format:	Patent
Sprache:	eng
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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