FESTPHASEANALYTISCHE VORRICHTUNG UND VERFAHREN ZU IHRER VERWENDUNG

A novel material and device useful in solid-phase binding assays to determine the presence or amount of an analyte in a test sample, particularly antigens or antibodies, is disclosed. The material comprises a porous matrix of fibers and a plurality of substantially spherical, solid particles having...

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Hauptverfasser: SAFFORD, SARAH E, HOFLER, JOHN G, KNIGGE, KEVIN M, BROWN, WILLIAM E., III, DEVEREAUX, SHARON M, CLEMENS, JOHN M
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creator SAFFORD, SARAH E
HOFLER, JOHN G
KNIGGE, KEVIN M
BROWN, WILLIAM E., III
DEVEREAUX, SHARON M
CLEMENS, JOHN M
description A novel material and device useful in solid-phase binding assays to determine the presence or amount of an analyte in a test sample, particularly antigens or antibodies, is disclosed. The material comprises a porous matrix of fibers and a plurality of substantially spherical, solid particles having an average diameter of from about 0.1 to about 5 microns. The particles are retained and immobilized upon the fibers of the matrix. Preferably, the particles have on their surfaces a substance capable of reaction with the analyte in the sample, and the average diameter of the particles is less than the average pore size of the matrix. The device, in a preferred embodiment, comprises a substantially planar layer of the described material.
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subjects INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
PHYSICS
TESTING
title FESTPHASEANALYTISCHE VORRICHTUNG UND VERFAHREN ZU IHRER VERWENDUNG
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