PHARMAZEUTISCHE ZUBEREITUNG FUER DIE INTRAREKTALE VERABREICHUNG VON CALCITONIN UND DARAUS HERGESTELLTE EINZELDOSISFORMEN
New compositions containing a calcitonin as the active ingredient are described which are suitable for the intrarectal administration as soft gelatin capsules or microenemas, wherein the active principle, optionally admixed with a stabilizer, is dissolved in a liquid vehicle consisting of : a) at le...
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| creator | LATTANZI, FILIPPO VANNI, RICCARDO |
| description | New compositions containing a calcitonin as the active ingredient are described which are suitable for the intrarectal administration as soft gelatin capsules or microenemas, wherein the active principle, optionally admixed with a stabilizer, is dissolved in a liquid vehicle consisting of : a) at least 70 % by weight of a polyethylene or a polypropylene glycol or a mixture of polyethylene or polypropylene glycols with different molecular weights, having the consistency of a homogeneous fluid at room temperature, and b) less than 15 % by weight of a buffer in a pH range of from 4.5 to 6.5, and optionally c) less than 15 % by weight of an alcohol of 2 to 6 carbon atoms containing two or more hydroxy groups. The new compositions, which do not contain any absorption aid, give calcitonin plasma levels comparable to a conventional intramuscular administration. |
| format | Patent |
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The new compositions, which do not contain any absorption aid, give calcitonin plasma levels comparable to a conventional intramuscular administration.</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1991</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNyrEKwjAQBuAuDqK-w72Agyii4zX9a4IxlculQ5dSJE6igg4-vgo-gNO3fOPidbQsB-6Q1EVjQV0qIXCawo7qBKHKgVxQYcFe2YNaCJefYuz3tE0gw944bYILlEJFFQunSBayQ1R4ryC40MFXTXSxbuSAMC1G5-HyyLOfk4JqqLHzfL_1-XEfTvmanz0r1tvlZqW6WP5R3rp9OyE</recordid><startdate>19911115</startdate><enddate>19911115</enddate><creator>LATTANZI, FILIPPO</creator><creator>VANNI, RICCARDO</creator><scope>EVB</scope></search><sort><creationdate>19911115</creationdate><title>PHARMAZEUTISCHE ZUBEREITUNG FUER DIE INTRAREKTALE VERABREICHUNG VON CALCITONIN UND DARAUS HERGESTELLTE EINZELDOSISFORMEN</title><author>LATTANZI, FILIPPO ; VANNI, RICCARDO</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_ATE69384TT13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; ger</language><creationdate>1991</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>LATTANZI, FILIPPO</creatorcontrib><creatorcontrib>VANNI, RICCARDO</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>LATTANZI, FILIPPO</au><au>VANNI, RICCARDO</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>PHARMAZEUTISCHE ZUBEREITUNG FUER DIE INTRAREKTALE VERABREICHUNG VON CALCITONIN UND DARAUS HERGESTELLTE EINZELDOSISFORMEN</title><date>1991-11-15</date><risdate>1991</risdate><abstract>New compositions containing a calcitonin as the active ingredient are described which are suitable for the intrarectal administration as soft gelatin capsules or microenemas, wherein the active principle, optionally admixed with a stabilizer, is dissolved in a liquid vehicle consisting of : a) at least 70 % by weight of a polyethylene or a polypropylene glycol or a mixture of polyethylene or polypropylene glycols with different molecular weights, having the consistency of a homogeneous fluid at room temperature, and b) less than 15 % by weight of a buffer in a pH range of from 4.5 to 6.5, and optionally c) less than 15 % by weight of an alcohol of 2 to 6 carbon atoms containing two or more hydroxy groups. The new compositions, which do not contain any absorption aid, give calcitonin plasma levels comparable to a conventional intramuscular administration.</abstract><edition>5</edition><oa>free_for_read</oa></addata></record> |
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| language | eng ; ger |
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| subjects | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | PHARMAZEUTISCHE ZUBEREITUNG FUER DIE INTRAREKTALE VERABREICHUNG VON CALCITONIN UND DARAUS HERGESTELLTE EINZELDOSISFORMEN |
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