CODON-OPTIMISIERTE HIV-RT-NEF-GAG DNA IMPFSTOFFE

THE INVENTION PROVIDES A NUCLEOTIDE SEQUENCE THAT ENCODES AN HIV-1 GAG PROTEIN OR FRAGMENT THEREOF CONTAINING A GAG EPITOPE AND A SECOND HIV ANTIGEN OR A FRAGMENT ENCODING AN EPITOPE OF SAID SECOND HIV ANTIGEN, OPERABLY LINKED TO A HETEROLOGOUS PROMOTER. PREFERRED POLYNUCLEOTIDE SEQUENCES FURTHER EN...

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Hauptverfasser: LEAR, ANDREW, ERTL, PETER, VAN WELY, CATHERINE, GOUGH, GERALD, BEATON, ANDREW, TITE, JOHN
Format: Patent
Sprache:ger
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Zusammenfassung:THE INVENTION PROVIDES A NUCLEOTIDE SEQUENCE THAT ENCODES AN HIV-1 GAG PROTEIN OR FRAGMENT THEREOF CONTAINING A GAG EPITOPE AND A SECOND HIV ANTIGEN OR A FRAGMENT ENCODING AN EPITOPE OF SAID SECOND HIV ANTIGEN, OPERABLY LINKED TO A HETEROLOGOUS PROMOTER. PREFERRED POLYNUCLEOTIDE SEQUENCES FURTHER ENCODES NEF OR A FRAGMENT THEREOF AND RT OR A FRAGMENT THEREOF.