NUKLEOTIDSEQUENZEN CODIEREND FÜR DEREGULIERTE PHOSPHOGLYCERAT-DEHYDROGENASEN CORYNEFORMER BAKTERIEN SOWIE VERFAHREN ZUR HERSTELLUNG VON L- SERIN

The invention relates to nucleotide sequences of coryneform bacteria that encode proteins that are involved in the biosynthesis of L-serine and to a method for producing L-serine. According to the invention, at least 79 amino acids at the C terminus of the wild-type serA sequence are deleted, thereb...

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Hauptverfasser: FAURIE, ROBERT, EGGELING, LOTHAR, SAHM, HERMANN, PETERS-WENDISCH, PETRA, NETZER, ROMAN, KLASSEN, BIRGIT
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creator FAURIE, ROBERT
EGGELING, LOTHAR
SAHM, HERMANN
PETERS-WENDISCH, PETRA
NETZER, ROMAN
KLASSEN, BIRGIT
description The invention relates to nucleotide sequences of coryneform bacteria that encode proteins that are involved in the biosynthesis of L-serine and to a method for producing L-serine. According to the invention, at least 79 amino acids at the C terminus of the wild-type serA sequence are deleted, thereby producing a 3-phosphoglycerate dehydrogenase having a reduced feedback inhibition by L-serine vis-à-vis the wild-type sequence.
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
title NUKLEOTIDSEQUENZEN CODIEREND FÜR DEREGULIERTE PHOSPHOGLYCERAT-DEHYDROGENASEN CORYNEFORMER BAKTERIEN SOWIE VERFAHREN ZUR HERSTELLUNG VON L- SERIN
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