PYRIDOPYRIMIDINONE ZUR BEHANDLUNG VON KREBSERKRANKUNGEN

PYRIDOPYRIMIDINONE ZUR BEHANDLUNG VON KREBSERKRANKUNGEN

The invention relates to compounds of formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, X and X' have the designations cited in patent claim 1. Said compounds are inhibitors of tyrosine kinases, especially TIE-2, and Raf kinases, and can, inter alia, be used for the treatment of tumors.

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Hauptverfasser: RAUTENBERG, WILFRIED, JONCZYK, ALFRED, SOLER RIERA, MARTA, MITJANS, FRANCESC, ROSELL-VIVES, ELISABET, ACKERMANN, KARL-AUGUST, ADAN, JAUME, HOELZEMANN, GUENTER, STAEHLE, WOLFGANG, CRASSIER, HELENE
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CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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creator RAUTENBERG, WILFRIED
JONCZYK, ALFRED
SOLER RIERA, MARTA
MITJANS, FRANCESC
ROSELL-VIVES, ELISABET
ACKERMANN, KARL-AUGUST
ADAN, JAUME
HOELZEMANN, GUENTER
STAEHLE, WOLFGANG
CRASSIER, HELENE
description The invention relates to compounds of formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, X and X' have the designations cited in patent claim 1. Said compounds are inhibitors of tyrosine kinases, especially TIE-2, and Raf kinases, and can, inter alia, be used for the treatment of tumors.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
title PYRIDOPYRIMIDINONE ZUR BEHANDLUNG VON KREBSERKRANKUNGEN
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