MEDIKAMENTE GEGEN ALZHEIMER-KRANKHEIT

MEDIKAMENTE GEGEN ALZHEIMER-KRANKHEIT

Novel multifunctional compound for the treatment or the retardation of neurodegenerative diseases e.g. Alzheimer's disease and related pathological conditions. Formula (I); wherein, R is a non-steroidal anti-inflammatory drug moiety, being selected from the category of acetic acid derivatives (...

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Hauptverfasser: KOUROUNAKIS, ANGELIKI, GALANAKIS, DIMITRIOS, DOULGKERIS, CHRISTOS, KOUROUNAKIS, PANOS
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creator KOUROUNAKIS, ANGELIKI
GALANAKIS, DIMITRIOS
DOULGKERIS, CHRISTOS
KOUROUNAKIS, PANOS
description Novel multifunctional compound for the treatment or the retardation of neurodegenerative diseases e.g. Alzheimer's disease and related pathological conditions. Formula (I); wherein, R is a non-steroidal anti-inflammatory drug moiety, being selected from the category of acetic acid derivatives (such as indomethacin), propionic acid derivatives (e.g. naproxen, ketoprofen) or various other acids with anti-inflammatory action which do not belong to the Above mentioned categories, A is a CHOH group or a CH2 group or a (CH2)2 group, Y is an antioxidant moiety (cysteamine or cysteine ethyl ester) or neuroprotective moiety (2-Pyridin-3-yl-alkanol) or NGF-inducing moiety (e.g. 2-methoxy-4-methyl-phenol).
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title MEDIKAMENTE GEGEN ALZHEIMER-KRANKHEIT
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