GESPANNTE, HELIXFORMENDE PEPTIDE UND VERFAHREN UM SIE HERZUSTELLEN
Provided are cyclized peptides with a constrained region(s) having an alpha -helical conformation. Constrained helical peptides having amino acid sequences from HIV gp41 are provided, as is their use in preparing antibodies that prevent viral membrane fusion. Also provided are methods for making suc...
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| creator | BRAISTED, ANDREW WELLS, JAMES, A STAROVASNIK, MELISSA, A PHELAN, J., CHRISTOPHER JUDICE, J., KEVIN MCDOWELL, ROBERT, S |
| description | Provided are cyclized peptides with a constrained region(s) having an alpha -helical conformation. Constrained helical peptides having amino acid sequences from HIV gp41 are provided, as is their use in preparing antibodies that prevent viral membrane fusion. Also provided are methods for making such cyclized peptides. |
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| subjects | CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | GESPANNTE, HELIXFORMENDE PEPTIDE UND VERFAHREN UM SIE HERZUSTELLEN |
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