PSEUDOTYPIERUNG VON HIV VEKTOREN MIT MOKOLA VIRENHÜLLEN

The invention relates to a defective lentivirus which is pseudotyped with a lyssavirus envelope of the PV (rabies virus) or MOK type (Mokola virus), for example, and to the use thereof, especially in the preparation of a composition for in vivo transfer of genes in astrocytes and also for the treatm...

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Bibliographische Detailangaben
Hauptverfasser: DUFOUR, NOELLE, HE, YI, SARKIS, CHAMSY, MALLET, JACQUES, SERGUERA, CHE
Format: Patent
Sprache:ger
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Zusammenfassung:The invention relates to a defective lentivirus which is pseudotyped with a lyssavirus envelope of the PV (rabies virus) or MOK type (Mokola virus), for example, and to the use thereof, especially in the preparation of a composition for in vivo transfer of genes in astrocytes and also for the treatment of disorders of the central nervous system.