BENZIMIDAZOLVERBINDUNGEN UND IHRE VERWENDUNG ALS GABA A RECEPTOR KOMPLEX MODULATOREN
The present patent application discloses compounds having the formula or a pharmaceutically acceptable salt thereof or an oxide thereof wherein R is wherein A, B and D each is CH, or one or two of A, B and D is N and the others are CH; R is phenyl, benzimidazolyl, or monocyclic heteroaryl all of whi...
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creator | TEUBER, LENE WAETJEN, FRANK |
description | The present patent application discloses compounds having the formula or a pharmaceutically acceptable salt thereof or an oxide thereof wherein R is wherein A, B and D each is CH, or one or two of A, B and D is N and the others are CH; R is phenyl, benzimidazolyl, or monocyclic heteroaryl all of which may be substituted one or more times with substituents selected from alkyl, alkoxy, phenyl, halogen, CF3, amino, nitro, cyano, acyl, acylamino, phenyl and monocyclic heteroaryl; and one of R and R is hydrogen and the other is furanyl or isoxazolyl each of which may be substituted one or more times with substituents selected from halogen, alkyl, alkoxy and phenyl. The compounds are useful for the treatment of various central nervous system disorders such as epilepsy and other convulsive disorders, anxiety, sleep disorders and memory disorders. |
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subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
title | BENZIMIDAZOLVERBINDUNGEN UND IHRE VERWENDUNG ALS GABA A RECEPTOR KOMPLEX MODULATOREN |
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