HYDROGELE ZUR ORTHOPÄDISCHEN REPARATUR

Hydrogels intended for orthopedic applications, including repair and regeneration of cartilage, bone, joint surfaces and related tissues, must possess greater strength and toughness than hydrogels used in soft tissue repair. A hydrogel formulation is provided which has high strength, toughness, a su...

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Hauptverfasser: COURY, ARTHUR, J, TRAVERSE, JOHN, F, AVILA, LUIS, Z, JARRETT, PETER, K, GOODRICH, STEPHEN, D, KRAMER, HILDEGARD, M
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creator COURY, ARTHUR, J
TRAVERSE, JOHN, F
AVILA, LUIS, Z
JARRETT, PETER, K
GOODRICH, STEPHEN, D
KRAMER, HILDEGARD, M
description Hydrogels intended for orthopedic applications, including repair and regeneration of cartilage, bone, joint surfaces and related tissues, must possess greater strength and toughness than hydrogels used in soft tissue repair. A hydrogel formulation is provided which has high strength, toughness, a suitable mechanical modulus and low equilibrium hydration. It may also have controlled porosity or degradation time. It can be made to polymerize in situ with high ("good" to "excellent") adherence to target tissue or surfaces. A preferred formulation for forming such gels comprises 40 to 80 % by weight of a low-molecular weight polar monomer and 30 to 10 % of a hydrophilic macromeric crosslinker.
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subjects CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES
CHEMISTRY
COMPOSITIONS BASED THEREON
DISINFECTION, STERILISATION, OR DEODORISATION OF AIR
HUMAN NECESSITIES
HYGIENE
MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVINGCARBON-TO-CARBON UNSATURATED BONDS
MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES
MEDICAL OR VETERINARY SCIENCE
METALLURGY
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL
ORGANIC MACROMOLECULAR COMPOUNDS
THEIR PREPARATION OR CHEMICAL WORKING-UP
title HYDROGELE ZUR ORTHOPÄDISCHEN REPARATUR
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