PARTIKULÄRE ZUSAMMENSETZUNG MIT SIGMOIDEM FREISETZUNGSMUSTER ENTHALTEND ELETRIPTAN HYDROBROMID

The invention provides a pharmaceutical composition in particulate form, suitable for oral administration, including a core containing eletriptan or a pharmaceutically acceptable salt thereof, the core being coated with a water-insoluble, permeable coating including one or more acrylic copolymer(s)...

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Hauptverfasser: MACRAE, ROSS J, WALTHER, MATHIAS, DE RASPIDE, MANAUD
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creator MACRAE, ROSS J
WALTHER, MATHIAS
DE RASPIDE, MANAUD
description The invention provides a pharmaceutical composition in particulate form, suitable for oral administration, including a core containing eletriptan or a pharmaceutically acceptable salt thereof, the core being coated with a water-insoluble, permeable coating including one or more acrylic copolymer(s) containing trimethylammoniumethylmethacrylate groups, said composition being capable of achieving a sigmoidal pattern of controlled drug release. Such a pharmaceutical composition is particularly useful in the prevention of migraine recurrence.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title PARTIKULÄRE ZUSAMMENSETZUNG MIT SIGMOIDEM FREISETZUNGSMUSTER ENTHALTEND ELETRIPTAN HYDROBROMID
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