PARTIKULÄRE ZUSAMMENSETZUNG MIT SIGMOIDEM FREISETZUNGSMUSTER ENTHALTEND ELETRIPTAN HYDROBROMID
The invention provides a pharmaceutical composition in particulate form, suitable for oral administration, including a core containing eletriptan or a pharmaceutically acceptable salt thereof, the core being coated with a water-insoluble, permeable coating including one or more acrylic copolymer(s)...
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creator | MACRAE, ROSS J WALTHER, MATHIAS DE RASPIDE, MANAUD |
description | The invention provides a pharmaceutical composition in particulate form, suitable for oral administration, including a core containing eletriptan or a pharmaceutically acceptable salt thereof, the core being coated with a water-insoluble, permeable coating including one or more acrylic copolymer(s) containing trimethylammoniumethylmethacrylate groups, said composition being capable of achieving a sigmoidal pattern of controlled drug release. Such a pharmaceutical composition is particularly useful in the prevention of migraine recurrence. |
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subjects | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
title | PARTIKULÄRE ZUSAMMENSETZUNG MIT SIGMOIDEM FREISETZUNGSMUSTER ENTHALTEND ELETRIPTAN HYDROBROMID |
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