OPTISCHE SPALTUNG VON 1-AZABICYLO(2.2.2)OCTAN-3- AMIN,2-(DIPHENYLMETHYL)-N-((2-METHOXY-5-(1- METHYLETHYL)PHENYL)METHYL)
PCT No. PCT/IB96/00648 Sec. 371 Date Dec. 16, 1997 Sec. 102(e) Date Dec. 16, 1997 PCT Filed Jul. 4, 1996 PCT Pub. No. WO97/03984 PCT Pub. Date Feb. 6, 1997A process for resolving 1-azabicyclo[2.2.2]octan-3-amine, (2-diphenylmethyl)-N-[[2-methoxy-5-(1-methylethyl)phenyl]methyl] in which 1-azabicyclo[...
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description | PCT No. PCT/IB96/00648 Sec. 371 Date Dec. 16, 1997 Sec. 102(e) Date Dec. 16, 1997 PCT Filed Jul. 4, 1996 PCT Pub. No. WO97/03984 PCT Pub. Date Feb. 6, 1997A process for resolving 1-azabicyclo[2.2.2]octan-3-amine, (2-diphenylmethyl)-N-[[2-methoxy-5-(1-methylethyl)phenyl]methyl] in which 1-azabicyclo[2.2.2]octan-3-amine, (2-diphenylmethyl)-N-[[2-methoxy-5-(1-methylethyl)phenyl]methyl] is reacted with 1R-(-)-10-camphorsulfonic acid in a solvent capable of dissolving both the foregoing reactants and selectively dissolving the camphorsulfonic acid salt of the corresponding (2R, 3R) enantiomer relative to the (2S, 3S) enantiomer. |
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Date Feb. 6, 1997A process for resolving 1-azabicyclo[2.2.2]octan-3-amine, (2-diphenylmethyl)-N-[[2-methoxy-5-(1-methylethyl)phenyl]methyl] in which 1-azabicyclo[2.2.2]octan-3-amine, (2-diphenylmethyl)-N-[[2-methoxy-5-(1-methylethyl)phenyl]methyl] is reacted with 1R-(-)-10-camphorsulfonic acid in a solvent capable of dissolving both the foregoing reactants and selectively dissolving the camphorsulfonic acid salt of the corresponding (2R, 3R) enantiomer relative to the (2S, 3S) enantiomer.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2003</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNyrEKwjAYBOAuDqK-Q9xS8Jc2pe4xRhNIk0B_xbiUInESLVTw9VXaB5AbjuO-afJ2HnUtlCS15waP9kBOzpIc-IVvtQjGUbb-JnUCuYUCCK-0XTGgO-2VtMFUElUwKViglMFvuXOAEmgOZPgGMOh05PNkcmvvfVyMPUuWe4lCQeyeTey79hof8dVwlKzMNlmGmBf_mA-O4ji9</recordid><startdate>20031015</startdate><enddate>20031015</enddate><creator>TICKNER, DEREK, L</creator><creator>MELTZ, MORGAN</creator><scope>EVB</scope></search><sort><creationdate>20031015</creationdate><title>OPTISCHE SPALTUNG VON 1-AZABICYLO(2.2.2)OCTAN-3- AMIN,2-(DIPHENYLMETHYL)-N-((2-METHOXY-5-(1- METHYLETHYL)PHENYL)METHYL)</title><author>TICKNER, DEREK, L ; MELTZ, MORGAN</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_ATE250600TT13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>ger</language><creationdate>2003</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>TICKNER, DEREK, L</creatorcontrib><creatorcontrib>MELTZ, MORGAN</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>TICKNER, DEREK, L</au><au>MELTZ, MORGAN</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>OPTISCHE SPALTUNG VON 1-AZABICYLO(2.2.2)OCTAN-3- AMIN,2-(DIPHENYLMETHYL)-N-((2-METHOXY-5-(1- METHYLETHYL)PHENYL)METHYL)</title><date>2003-10-15</date><risdate>2003</risdate><abstract>PCT No. PCT/IB96/00648 Sec. 371 Date Dec. 16, 1997 Sec. 102(e) Date Dec. 16, 1997 PCT Filed Jul. 4, 1996 PCT Pub. No. WO97/03984 PCT Pub. Date Feb. 6, 1997A process for resolving 1-azabicyclo[2.2.2]octan-3-amine, (2-diphenylmethyl)-N-[[2-methoxy-5-(1-methylethyl)phenyl]methyl] in which 1-azabicyclo[2.2.2]octan-3-amine, (2-diphenylmethyl)-N-[[2-methoxy-5-(1-methylethyl)phenyl]methyl] is reacted with 1R-(-)-10-camphorsulfonic acid in a solvent capable of dissolving both the foregoing reactants and selectively dissolving the camphorsulfonic acid salt of the corresponding (2R, 3R) enantiomer relative to the (2S, 3S) enantiomer.</abstract><edition>7</edition><oa>free_for_read</oa></addata></record> |
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subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
title | OPTISCHE SPALTUNG VON 1-AZABICYLO(2.2.2)OCTAN-3- AMIN,2-(DIPHENYLMETHYL)-N-((2-METHOXY-5-(1- METHYLETHYL)PHENYL)METHYL) |
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