PHENOXYPHENYLESSIGSÄUREDERIVATE

Phenoxyphenylacetic acids and derivatives of the general structural formula I have endothelin antagonist activity and are useful in treating cardiovascular disorders, such as hypertension, postischemic renal failure, vasospasm, cerebral and cardiac ischemia, myocardial infarction, endotoxic shock, b...

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Bibliographische Detailangaben
Hauptverfasser:	WALSH, THOMAS F, FITCH, KENNETH J, GREENLEE, WILLIAM J, BAGLEY, SCOTT W, TATA, JAMES R, PETTIBONE, DOUGLAS J, DHANOA, DALJIT S, BROTEN, THEODORE P, RIVERO, RALPH A, WILLIAMS, DAVID L, CHAKRAVARTY, PRASUN K, KEVIN, NANCY JO
Format:	Patent
Sprache:	ger
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Phenoxyphenylacetic acids and derivatives of the general structural formula I have endothelin antagonist activity and are useful in treating cardiovascular disorders, such as hypertension, postischemic renal failure, vasospasm, cerebral and cardiac ischemia, myocardial infarction, endotoxic shock, benign prostatic hyperplasia, inflammatory diseases including Raynaud's disease and asthma.