ZUSAMMENSETZUNGEN UND VERFAHREN ZUR BEHANDLUNG VON DURCH MAST-ZELLEN VERURSACHTEN KRANKHEITEN

The present invention describes compounds, methods and compositions effective to treat mast cell mediated inflammatory conditions, such as conjunctivitis, asthma and allergic rhinitis. The compounds of the invention comprise novel mono- and di-aminomethylbenzyl, aminobenzyl, guanidylbenzyl and benzy...

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Hauptverfasser: GSCHWEND, HEINZ, W, KUO, ELAINE, LUM, ROBERT, T, BAUER, BARR, E, RICE, KEN
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creator GSCHWEND, HEINZ, W
KUO, ELAINE
LUM, ROBERT, T
BAUER, BARR, E
RICE, KEN
description The present invention describes compounds, methods and compositions effective to treat mast cell mediated inflammatory conditions, such as conjunctivitis, asthma and allergic rhinitis. The compounds of the invention comprise novel mono- and di-aminomethylbenzyl, aminobenzyl, guanidylbenzyl and benzyl tryptase inhibitors. The compositions for treating mast cell mediated inflammatory conditions include oral, inhalant and topical preparations as well as devices comprising such preparations.
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subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title ZUSAMMENSETZUNGEN UND VERFAHREN ZUR BEHANDLUNG VON DURCH MAST-ZELLEN VERURSACHTEN KRANKHEITEN
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