MULTIVALENTE EINKETTIGE ANTIKÖRPER

The present invention discloses multivalent single chain antibodies which have two or more biologically active antigen binding sites. The multivalent single chain antibodies are formed by using a peptide linker to covalently link two or more single chain antibodies, each single chain antibody having...

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Bibliographische Detailangaben
Hauptverfasser: GOURLIE, BRIAN, B, MEZES, PETER, S
Format: Patent
Sprache:ger
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Beschreibung
Zusammenfassung:The present invention discloses multivalent single chain antibodies which have two or more biologically active antigen binding sites. The multivalent single chain antibodies are formed by using a peptide linker to covalently link two or more single chain antibodies, each single chain antibody having a variable light domain linked to a variable heavy chain domain by a peptide linker.