ANTIVIRAL WIRKSAME PHARMAZEUTISCHE ÖL IN WASSER- EMULSION, DIE 9-((2-HYDROXYETHOXY)METHYL>-GUANIN (ACYCLOVIR) ODER EIN SALZ ODER EINEN ESTER DAVON ENTHÄLT
An antivirally active pharmaceutical oil-in-water emulsion containing 9-[(2-hydroxyethoxy)methyl]guanine (acyclovir) or a salt or ester thereof as an active ingredient in the continuous aqueous phase, said phase in addition to said active ingredient and the dispersed oil phase containing a water mis...
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| creator | GEBHARD-HANSEN, KNUD ERIK LISSAU, BODIL GYLLEMBOURG ALHEDE, BORGE INGVAR FRISCH BJORNSDOTTIR, KAREN PEDERSEN, SOREN BOLS |
| description | An antivirally active pharmaceutical oil-in-water emulsion containing 9-[(2-hydroxyethoxy)methyl]guanine (acyclovir) or a salt or ester thereof as an active ingredient in the continuous aqueous phase, said phase in addition to said active ingredient and the dispersed oil phase containing a water miscible organic solvent, wherein a polyhydric alcohol may form a constituent. The emulsion comprises from 1 % to 10 % w/w of acyclovir or a salt or ester thereof, from 20 % to 50 % w/w of organic solvent comprising from 5 % to 50 % w/w glycerol formal and from 0 % to 29 % w/w of a polyhydric alcohol, and from 20 % to 40 % w/w water, said percentages being based on the total weight of the formulation. As a polyhydric alcohol propylene glycol may be used, and the emulsion may be available as a cream, wherein the oil phase comprises white vaseline, liquid paraffin (paraffin oil), glycerol monostearate, and stearic acid. |
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The emulsion comprises from 1 % to 10 % w/w of acyclovir or a salt or ester thereof, from 20 % to 50 % w/w of organic solvent comprising from 5 % to 50 % w/w glycerol formal and from 0 % to 29 % w/w of a polyhydric alcohol, and from 20 % to 40 % w/w water, said percentages being based on the total weight of the formulation. As a polyhydric alcohol propylene glycol may be used, and the emulsion may be available as a cream, wherein the oil phase comprises white vaseline, liquid paraffin (paraffin oil), glycerol monostearate, and stearic acid.</description><edition>6</edition><language>ger</language><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS ; CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>1996</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19960515&DB=EPODOC&CC=AT&NR=E137113T1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25544,76293</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19960515&DB=EPODOC&CC=AT&NR=E137113T1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>GEBHARD-HANSEN, KNUD ERIK</creatorcontrib><creatorcontrib>LISSAU, BODIL GYLLEMBOURG</creatorcontrib><creatorcontrib>ALHEDE, BORGE INGVAR FRISCH</creatorcontrib><creatorcontrib>BJORNSDOTTIR, KAREN</creatorcontrib><creatorcontrib>PEDERSEN, SOREN BOLS</creatorcontrib><title>ANTIVIRAL WIRKSAME PHARMAZEUTISCHE ÖL IN WASSER- EMULSION, DIE 9-((2-HYDROXYETHOXY)METHYL>-GUANIN (ACYCLOVIR) ODER EIN SALZ ODER EINEN ESTER DAVON ENTHÄLT</title><description>An antivirally active pharmaceutical oil-in-water emulsion containing 9-[(2-hydroxyethoxy)methyl]guanine (acyclovir) or a salt or ester thereof as an active ingredient in the continuous aqueous phase, said phase in addition to said active ingredient and the dispersed oil phase containing a water miscible organic solvent, wherein a polyhydric alcohol may form a constituent. The emulsion comprises from 1 % to 10 % w/w of acyclovir or a salt or ester thereof, from 20 % to 50 % w/w of organic solvent comprising from 5 % to 50 % w/w glycerol formal and from 0 % to 29 % w/w of a polyhydric alcohol, and from 20 % to 40 % w/w water, said percentages being based on the total weight of the formulation. As a polyhydric alcohol propylene glycol may be used, and the emulsion may be available as a cream, wherein the oil phase comprises white vaseline, liquid paraffin (paraffin oil), glycerol monostearate, and stearic acid.</description><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS</subject><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1996</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNTbsOAUEU3UYh-IerW4kp1haikdzsXmZidkZm7mI1IjIqQcIn-AaVv_FjphC15rxyTk47eaFhtVIONayVW3isCJYSXYVbqln5QhK8nxqUgTV6T04AVbX2ypohlIpgItJ0JGRTOrtpiGXEQRW50VMxr9HEYYpFU2gbXwZgS3JAMfSotz9HBshz1CWubNSG5fuhuZu0jvvTLfS-3En6M-JCinC97MLtuj-Ec7jvkCnLx1mWM2f5P50PN_JFhA</recordid><startdate>19960515</startdate><enddate>19960515</enddate><creator>GEBHARD-HANSEN, KNUD ERIK</creator><creator>LISSAU, BODIL GYLLEMBOURG</creator><creator>ALHEDE, BORGE INGVAR FRISCH</creator><creator>BJORNSDOTTIR, KAREN</creator><creator>PEDERSEN, SOREN BOLS</creator><scope>EVB</scope></search><sort><creationdate>19960515</creationdate><title>ANTIVIRAL WIRKSAME PHARMAZEUTISCHE ÖL IN WASSER- EMULSION, DIE 9-((2-HYDROXYETHOXY)METHYL>-GUANIN (ACYCLOVIR) ODER EIN SALZ ODER EINEN ESTER DAVON ENTHÄLT</title><author>GEBHARD-HANSEN, KNUD ERIK ; LISSAU, BODIL GYLLEMBOURG ; ALHEDE, BORGE INGVAR FRISCH ; BJORNSDOTTIR, KAREN ; PEDERSEN, SOREN BOLS</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_ATE137113TT13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>ger</language><creationdate>1996</creationdate><topic>ACYCLIC OR CARBOCYCLIC COMPOUNDS</topic><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>GEBHARD-HANSEN, KNUD ERIK</creatorcontrib><creatorcontrib>LISSAU, BODIL GYLLEMBOURG</creatorcontrib><creatorcontrib>ALHEDE, BORGE INGVAR FRISCH</creatorcontrib><creatorcontrib>BJORNSDOTTIR, KAREN</creatorcontrib><creatorcontrib>PEDERSEN, SOREN BOLS</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>GEBHARD-HANSEN, KNUD ERIK</au><au>LISSAU, BODIL GYLLEMBOURG</au><au>ALHEDE, BORGE INGVAR FRISCH</au><au>BJORNSDOTTIR, KAREN</au><au>PEDERSEN, SOREN BOLS</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>ANTIVIRAL WIRKSAME PHARMAZEUTISCHE ÖL IN WASSER- EMULSION, DIE 9-((2-HYDROXYETHOXY)METHYL>-GUANIN (ACYCLOVIR) ODER EIN SALZ ODER EINEN ESTER DAVON ENTHÄLT</title><date>1996-05-15</date><risdate>1996</risdate><abstract>An antivirally active pharmaceutical oil-in-water emulsion containing 9-[(2-hydroxyethoxy)methyl]guanine (acyclovir) or a salt or ester thereof as an active ingredient in the continuous aqueous phase, said phase in addition to said active ingredient and the dispersed oil phase containing a water miscible organic solvent, wherein a polyhydric alcohol may form a constituent. The emulsion comprises from 1 % to 10 % w/w of acyclovir or a salt or ester thereof, from 20 % to 50 % w/w of organic solvent comprising from 5 % to 50 % w/w glycerol formal and from 0 % to 29 % w/w of a polyhydric alcohol, and from 20 % to 40 % w/w water, said percentages being based on the total weight of the formulation. As a polyhydric alcohol propylene glycol may be used, and the emulsion may be available as a cream, wherein the oil phase comprises white vaseline, liquid paraffin (paraffin oil), glycerol monostearate, and stearic acid.</abstract><edition>6</edition><oa>free_for_read</oa></addata></record> |
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| subjects | ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| title | ANTIVIRAL WIRKSAME PHARMAZEUTISCHE ÖL IN WASSER- EMULSION, DIE 9-((2-HYDROXYETHOXY)METHYL>-GUANIN (ACYCLOVIR) ODER EIN SALZ ODER EINEN ESTER DAVON ENTHÄLT |
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