PYRIMIDINDERIVATE
The compounds of the general formula I (I) and pharmaceutically acceptable acid addition salts and hydrates thereof possess useful immunostimulant properties and can be used in therapy. In the general Formula I A stands for -CH2-CH2-, -CH2-CH2-CH2-, -CH2-CH2-CH2CH2-or -CH=CH-; R4 is hydrogen, C1-4 a...
Gespeichert in:
| Hauptverfasser: | , , , , , |
|---|---|
| Format: | Patent |
| Sprache: | ger |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | MAGYAR KAROLY DR BOZSING DANIEL . DR BERENYI EDIT . DR KOVANYI GYOERGYI . DR TUBOLY SANDOR DR MANDI ATTILA . DR |
| description | The compounds of the general formula I (I) and pharmaceutically acceptable acid addition salts and hydrates thereof possess useful immunostimulant properties and can be used in therapy. In the general Formula I A stands for -CH2-CH2-, -CH2-CH2-CH2-, -CH2-CH2-CH2CH2-or -CH=CH-; R4 is hydrogen, C1-4 alkyl or optionally substituted phenyl; r is 0, 1, 2, 3 or 4; R1 stands for hydrogen of C1-5 alkanoyl; R2 represents hydrogen, C1-5 alkanoyl or a group of the general formula (a) (a) wherein R stands for hydrogen, C1-4 alkyl, C2-4 alkenyl, phenyl or phenyl-C1-3 alkyl and R3 stands for hydrogen. The compounds of the general Formula I can be prepared by reacting a 2-mercapto-4,6-diamino-pyrimidine of the general Formula II (II) with a dihalo compound of the general Formula III (III) (wherein Y and Z are halogen). |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_ATA345187A</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>ATA345187A</sourcerecordid><originalsourceid>FETCH-epo_espacenet_ATA345187A3</originalsourceid><addsrcrecordid>eNrjZBAMiAzy9PV08fRzcQ3yDHMMceVhYE1LzClO5YXS3Azybq4hzh66qQX58anFBYnJqXmpJfGOIY7GJqaGFuaOxoRVAADK6B1f</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>PYRIMIDINDERIVATE</title><source>esp@cenet</source><creator>MAGYAR KAROLY DR ; BOZSING DANIEL . DR ; BERENYI EDIT . DR ; KOVANYI GYOERGYI . DR ; TUBOLY SANDOR DR ; MANDI ATTILA . DR</creator><creatorcontrib>MAGYAR KAROLY DR ; BOZSING DANIEL . DR ; BERENYI EDIT . DR ; KOVANYI GYOERGYI . DR ; TUBOLY SANDOR DR ; MANDI ATTILA . DR</creatorcontrib><description>The compounds of the general formula I (I) and pharmaceutically acceptable acid addition salts and hydrates thereof possess useful immunostimulant properties and can be used in therapy. In the general Formula I A stands for -CH2-CH2-, -CH2-CH2-CH2-, -CH2-CH2-CH2CH2-or -CH=CH-; R4 is hydrogen, C1-4 alkyl or optionally substituted phenyl; r is 0, 1, 2, 3 or 4; R1 stands for hydrogen of C1-5 alkanoyl; R2 represents hydrogen, C1-5 alkanoyl or a group of the general formula (a) (a) wherein R stands for hydrogen, C1-4 alkyl, C2-4 alkenyl, phenyl or phenyl-C1-3 alkyl and R3 stands for hydrogen. The compounds of the general Formula I can be prepared by reacting a 2-mercapto-4,6-diamino-pyrimidine of the general Formula II (II) with a dihalo compound of the general Formula III (III) (wherein Y and Z are halogen).</description><edition>5</edition><language>ger</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; METALLURGY ; ORGANIC CHEMISTRY</subject><creationdate>1993</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19931115&DB=EPODOC&CC=AT&NR=A345187A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,309,781,886,25569,76552</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19931115&DB=EPODOC&CC=AT&NR=A345187A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>MAGYAR KAROLY DR</creatorcontrib><creatorcontrib>BOZSING DANIEL . DR</creatorcontrib><creatorcontrib>BERENYI EDIT . DR</creatorcontrib><creatorcontrib>KOVANYI GYOERGYI . DR</creatorcontrib><creatorcontrib>TUBOLY SANDOR DR</creatorcontrib><creatorcontrib>MANDI ATTILA . DR</creatorcontrib><title>PYRIMIDINDERIVATE</title><description>The compounds of the general formula I (I) and pharmaceutically acceptable acid addition salts and hydrates thereof possess useful immunostimulant properties and can be used in therapy. In the general Formula I A stands for -CH2-CH2-, -CH2-CH2-CH2-, -CH2-CH2-CH2CH2-or -CH=CH-; R4 is hydrogen, C1-4 alkyl or optionally substituted phenyl; r is 0, 1, 2, 3 or 4; R1 stands for hydrogen of C1-5 alkanoyl; R2 represents hydrogen, C1-5 alkanoyl or a group of the general formula (a) (a) wherein R stands for hydrogen, C1-4 alkyl, C2-4 alkenyl, phenyl or phenyl-C1-3 alkyl and R3 stands for hydrogen. The compounds of the general Formula I can be prepared by reacting a 2-mercapto-4,6-diamino-pyrimidine of the general Formula II (II) with a dihalo compound of the general Formula III (III) (wherein Y and Z are halogen).</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1993</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZBAMiAzy9PV08fRzcQ3yDHMMceVhYE1LzClO5YXS3Azybq4hzh66qQX58anFBYnJqXmpJfGOIY7GJqaGFuaOxoRVAADK6B1f</recordid><startdate>19931115</startdate><enddate>19931115</enddate><creator>MAGYAR KAROLY DR</creator><creator>BOZSING DANIEL . DR</creator><creator>BERENYI EDIT . DR</creator><creator>KOVANYI GYOERGYI . DR</creator><creator>TUBOLY SANDOR DR</creator><creator>MANDI ATTILA . DR</creator><scope>EVB</scope></search><sort><creationdate>19931115</creationdate><title>PYRIMIDINDERIVATE</title><author>MAGYAR KAROLY DR ; BOZSING DANIEL . DR ; BERENYI EDIT . DR ; KOVANYI GYOERGYI . DR ; TUBOLY SANDOR DR ; MANDI ATTILA . DR</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_ATA345187A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>ger</language><creationdate>1993</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><toplevel>online_resources</toplevel><creatorcontrib>MAGYAR KAROLY DR</creatorcontrib><creatorcontrib>BOZSING DANIEL . DR</creatorcontrib><creatorcontrib>BERENYI EDIT . DR</creatorcontrib><creatorcontrib>KOVANYI GYOERGYI . DR</creatorcontrib><creatorcontrib>TUBOLY SANDOR DR</creatorcontrib><creatorcontrib>MANDI ATTILA . DR</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>MAGYAR KAROLY DR</au><au>BOZSING DANIEL . DR</au><au>BERENYI EDIT . DR</au><au>KOVANYI GYOERGYI . DR</au><au>TUBOLY SANDOR DR</au><au>MANDI ATTILA . DR</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>PYRIMIDINDERIVATE</title><date>1993-11-15</date><risdate>1993</risdate><abstract>The compounds of the general formula I (I) and pharmaceutically acceptable acid addition salts and hydrates thereof possess useful immunostimulant properties and can be used in therapy. In the general Formula I A stands for -CH2-CH2-, -CH2-CH2-CH2-, -CH2-CH2-CH2CH2-or -CH=CH-; R4 is hydrogen, C1-4 alkyl or optionally substituted phenyl; r is 0, 1, 2, 3 or 4; R1 stands for hydrogen of C1-5 alkanoyl; R2 represents hydrogen, C1-5 alkanoyl or a group of the general formula (a) (a) wherein R stands for hydrogen, C1-4 alkyl, C2-4 alkenyl, phenyl or phenyl-C1-3 alkyl and R3 stands for hydrogen. The compounds of the general Formula I can be prepared by reacting a 2-mercapto-4,6-diamino-pyrimidine of the general Formula II (II) with a dihalo compound of the general Formula III (III) (wherein Y and Z are halogen).</abstract><edition>5</edition><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | ger |
| recordid | cdi_epo_espacenet_ATA345187A |
| source | esp@cenet |
| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY |
| title | PYRIMIDINDERIVATE |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-15T15%3A40%3A44IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=MAGYAR%20KAROLY%20DR&rft.date=1993-11-15&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EATA345187A%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |