PROCESO PARA FABRICAR PÉPTIDOS MACROCÍCLICOS

La invención proporciona un proceso novedoso para fabricar un compuesto de fórmula (1), o una sal de este, en donde PG¹, PG² y PG³ son grupos protectores amino. El proceso de acuerdo con la invención es particularmente adecuado para la fabricación a gran escala en condiciones de GMP. The invention p...

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Hauptverfasser: MICHEL - BLISS, FRITZ, LARSSON, ULF GOERAN, HOFFMANN-EMERY, FABIENNE ROXANE, PUENTENER, KURT, ADAM, JEAN, DOTT, PASCAL JEAN CLAUDE
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creator MICHEL - BLISS, FRITZ
LARSSON, ULF GOERAN
HOFFMANN-EMERY, FABIENNE ROXANE
PUENTENER, KURT
ADAM, JEAN
DOTT, PASCAL JEAN CLAUDE
description La invención proporciona un proceso novedoso para fabricar un compuesto de fórmula (1), o una sal de este, en donde PG¹, PG² y PG³ son grupos protectores amino. El proceso de acuerdo con la invención es particularmente adecuado para la fabricación a gran escala en condiciones de GMP. The invention provides a novel process for manufacturing a compound of formula (I), or a salt thereof, wherein PG1, PG2 and PG3 are amino protective groups. The process according to the invention is particularly suitable for large-scale manufacturing under GMP conditions.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
title PROCESO PARA FABRICAR PÉPTIDOS MACROCÍCLICOS
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