SALES DE ACIDO NAFTALEN -1,5- DISULFONICO DE UN COMPUESTO DE 4- AMINO -1- ( PIRIDILMETIL) PIPERIDINA
La presente provee sales de ácido naftalen-1,5-disulfónico de 4-{N-[7-(3-(S)-1-carbamil-1,1-difenilmetil)pirrolidin-1-il)hept-1-il]-N-(isopropil)amino}-1-(4-metoxipirid-3-ilmetil)piperidina que son útiles como antagonistas de receptores muscarínicos. También se relaciona con composiciones farmacéuti...
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| creator | MAMMEN, MATHAI CHAO, ROBERT ZHANG, WEIJIANG WILSON, RICHARD CONGDON, JULIE |
| description | La presente provee sales de ácido naftalen-1,5-disulfónico de 4-{N-[7-(3-(S)-1-carbamil-1,1-difenilmetil)pirrolidin-1-il)hept-1-il]-N-(isopropil)amino}-1-(4-metoxipirid-3-ilmetil)piperidina que son útiles como antagonistas de receptores muscarínicos. También se relaciona con composiciones farmacéuticas que comprenden estas formas de sales, con métodos para usar estas formas de sales para tratar condiciones médicas mediadas por receptores muscarínicos; y con procesos para preparar estas formas de sales.
This invention provides naphthalene-1,5-disulfonic acid salts of 4-{N-[7-(3-(S)-1-carbamoyl-1,1-diphenylmethyl)pyrrolidin-1-yl)hept-1-yl]-N-(isopropyl)amino}-1-(4-methoxypyrid-3-ylmethyl)piperidine, which salts are useful as muscarinic receptor antagonists. This invention is also directed to pharmaceutical compositions comprising these salt forms, methods of using these salt forms for treating medical conditions mediated by muscarinic receptors; and processes for preparing these salt forms. |
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This invention provides naphthalene-1,5-disulfonic acid salts of 4-{N-[7-(3-(S)-1-carbamoyl-1,1-diphenylmethyl)pyrrolidin-1-yl)hept-1-yl]-N-(isopropyl)amino}-1-(4-methoxypyrid-3-ylmethyl)piperidine, which salts are useful as muscarinic receptor antagonists. This invention is also directed to pharmaceutical compositions comprising these salt forms, methods of using these salt forms for treating medical conditions mediated by muscarinic receptors; and processes for preparing these salt forms.</description><edition>7</edition><language>spa</language><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS ; CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>2005</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20051207&DB=EPODOC&CC=AR&NR=046427A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20051207&DB=EPODOC&CC=AR&NR=046427A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>MAMMEN, MATHAI</creatorcontrib><creatorcontrib>CHAO, ROBERT</creatorcontrib><creatorcontrib>ZHANG, WEIJIANG</creatorcontrib><creatorcontrib>WILSON, RICHARD</creatorcontrib><creatorcontrib>CONGDON, JULIE</creatorcontrib><title>SALES DE ACIDO NAFTALEN -1,5- DISULFONICO DE UN COMPUESTO DE 4- AMINO -1- ( PIRIDILMETIL) PIPERIDINA</title><description>La presente provee sales de ácido naftalen-1,5-disulfónico de 4-{N-[7-(3-(S)-1-carbamil-1,1-difenilmetil)pirrolidin-1-il)hept-1-il]-N-(isopropil)amino}-1-(4-metoxipirid-3-ilmetil)piperidina que son útiles como antagonistas de receptores muscarínicos. También se relaciona con composiciones farmacéuticas que comprenden estas formas de sales, con métodos para usar estas formas de sales para tratar condiciones médicas mediadas por receptores muscarínicos; y con procesos para preparar estas formas de sales.
This invention provides naphthalene-1,5-disulfonic acid salts of 4-{N-[7-(3-(S)-1-carbamoyl-1,1-diphenylmethyl)pyrrolidin-1-yl)hept-1-yl]-N-(isopropyl)amino}-1-(4-methoxypyrid-3-ylmethyl)piperidine, which salts are useful as muscarinic receptor antagonists. This invention is also directed to pharmaceutical compositions comprising these salt forms, methods of using these salt forms for treating medical conditions mediated by muscarinic receptors; and processes for preparing these salt forms.</description><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS</subject><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2005</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqFyjsLwjAUhuEuDqL-Bs-oYMDaqvMhFzyQS2mSuRSNk2ih_n9Mxd3p4_l458XNo5YehATkJBxYVCE_Fli5OzIQ5KNWzhJ3UxMtcGeaKH34umaAhqzLNYMNNNSSIG1kIL3NauRki8tidu8fY1r9dlGslQz8wtLw6tI49Nf0TO8O2319qg9nLKv_xQd2-jHC</recordid><startdate>20051207</startdate><enddate>20051207</enddate><creator>MAMMEN, MATHAI</creator><creator>CHAO, ROBERT</creator><creator>ZHANG, WEIJIANG</creator><creator>WILSON, RICHARD</creator><creator>CONGDON, JULIE</creator><scope>EVB</scope></search><sort><creationdate>20051207</creationdate><title>SALES DE ACIDO NAFTALEN -1,5- DISULFONICO DE UN COMPUESTO DE 4- AMINO -1- ( PIRIDILMETIL) PIPERIDINA</title><author>MAMMEN, MATHAI ; CHAO, ROBERT ; ZHANG, WEIJIANG ; WILSON, RICHARD ; CONGDON, JULIE</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_AR046427A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>spa</language><creationdate>2005</creationdate><topic>ACYCLIC OR CARBOCYCLIC COMPOUNDS</topic><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>MAMMEN, MATHAI</creatorcontrib><creatorcontrib>CHAO, ROBERT</creatorcontrib><creatorcontrib>ZHANG, WEIJIANG</creatorcontrib><creatorcontrib>WILSON, RICHARD</creatorcontrib><creatorcontrib>CONGDON, JULIE</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>MAMMEN, MATHAI</au><au>CHAO, ROBERT</au><au>ZHANG, WEIJIANG</au><au>WILSON, RICHARD</au><au>CONGDON, JULIE</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>SALES DE ACIDO NAFTALEN -1,5- DISULFONICO DE UN COMPUESTO DE 4- AMINO -1- ( PIRIDILMETIL) PIPERIDINA</title><date>2005-12-07</date><risdate>2005</risdate><abstract>La presente provee sales de ácido naftalen-1,5-disulfónico de 4-{N-[7-(3-(S)-1-carbamil-1,1-difenilmetil)pirrolidin-1-il)hept-1-il]-N-(isopropil)amino}-1-(4-metoxipirid-3-ilmetil)piperidina que son útiles como antagonistas de receptores muscarínicos. También se relaciona con composiciones farmacéuticas que comprenden estas formas de sales, con métodos para usar estas formas de sales para tratar condiciones médicas mediadas por receptores muscarínicos; y con procesos para preparar estas formas de sales.
This invention provides naphthalene-1,5-disulfonic acid salts of 4-{N-[7-(3-(S)-1-carbamoyl-1,1-diphenylmethyl)pyrrolidin-1-yl)hept-1-yl]-N-(isopropyl)amino}-1-(4-methoxypyrid-3-ylmethyl)piperidine, which salts are useful as muscarinic receptor antagonists. This invention is also directed to pharmaceutical compositions comprising these salt forms, methods of using these salt forms for treating medical conditions mediated by muscarinic receptors; and processes for preparing these salt forms.</abstract><edition>7</edition><oa>free_for_read</oa></addata></record> |
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| subjects | ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| title | SALES DE ACIDO NAFTALEN -1,5- DISULFONICO DE UN COMPUESTO DE 4- AMINO -1- ( PIRIDILMETIL) PIPERIDINA |
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