A process for the preparation of 1, 2, 4-trioxolane antimalarials

This invention relates to an improved process for the preparation of compounds of Formula I, salts of the free base cis-adamantane-2-spiro-3′-8′-[[[(2′-amino-2′-methylpropyl)amino]carbonyl]methyl]-1′,2′,4′-trioxaspiro[4.5]decane, Formula (I) wherein X is an anion. The compounds of Formula (I) have a...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	DORWAL HARISH N, TANWAR POOJA, YADAV GYAN CHAND
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

container_end_page
container_issue
container_start_page
container_title
container_volume
creator	DORWAL HARISH N TANWAR POOJA YADAV GYAN CHAND
description	This invention relates to an improved process for the preparation of compounds of Formula I, salts of the free base cis-adamantane-2-spiro-3′-8′-[[[(2′-amino-2′-methylpropyl)amino]carbonyl]methyl]-1′,2′,4′-trioxaspiro[4.5]decane, Formula (I) wherein X is an anion. The compounds of Formula (I) have antimalarial activity.
format	Patent
fullrecord	<record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_AP2011005946A0</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>AP2011005946A0</sourcerecordid><originalsourceid>FETCH-epo_espacenet_AP2011005946A03</originalsourceid><addsrcrecordid>eNrjZHB0VCgoyk9OLS5WSMsvUijJSAXyUwsSixJLMvPzFPLTFAx1FIx0FEx0S4oy8yvycxLzUhUS80oycxNzEosyE3OKeRhY04BUKi-U5mZQdnMNcfbQTS3Ij08tLkhMTs1LLYl3DDAyMDQ0MDC1NDFzNDAmThUADpMxCQ</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>A process for the preparation of 1, 2, 4-trioxolane antimalarials</title><source>esp@cenet</source><creator>DORWAL HARISH N ; TANWAR POOJA ; YADAV GYAN CHAND</creator><creatorcontrib>DORWAL HARISH N ; TANWAR POOJA ; YADAV GYAN CHAND</creatorcontrib><description>This invention relates to an improved process for the preparation of compounds of Formula I, salts of the free base cis-adamantane-2-spiro-3′-8′-[[[(2′-amino-2′-methylpropyl)amino]carbonyl]methyl]-1′,2′,4′-trioxaspiro[4.5]decane, Formula (I) wherein X is an anion. The compounds of Formula (I) have antimalarial activity.</description><language>eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; METALLURGY ; ORGANIC CHEMISTRY</subject><creationdate>2011</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20111031&DB=EPODOC&CC=AP&NR=2011005946A0$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76516</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20111031&DB=EPODOC&CC=AP&NR=2011005946A0$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>DORWAL HARISH N</creatorcontrib><creatorcontrib>TANWAR POOJA</creatorcontrib><creatorcontrib>YADAV GYAN CHAND</creatorcontrib><title>A process for the preparation of 1, 2, 4-trioxolane antimalarials</title><description>This invention relates to an improved process for the preparation of compounds of Formula I, salts of the free base cis-adamantane-2-spiro-3′-8′-[[[(2′-amino-2′-methylpropyl)amino]carbonyl]methyl]-1′,2′,4′-trioxaspiro[4.5]decane, Formula (I) wherein X is an anion. The compounds of Formula (I) have antimalarial activity.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2011</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZHB0VCgoyk9OLS5WSMsvUijJSAXyUwsSixJLMvPzFPLTFAx1FIx0FEx0S4oy8yvycxLzUhUS80oycxNzEosyE3OKeRhY04BUKi-U5mZQdnMNcfbQTS3Ij08tLkhMTs1LLYl3DDAyMDQ0MDC1NDFzNDAmThUADpMxCQ</recordid><startdate>20111031</startdate><enddate>20111031</enddate><creator>DORWAL HARISH N</creator><creator>TANWAR POOJA</creator><creator>YADAV GYAN CHAND</creator><scope>EVB</scope></search><sort><creationdate>20111031</creationdate><title>A process for the preparation of 1, 2, 4-trioxolane antimalarials</title><author>DORWAL HARISH N ; TANWAR POOJA ; YADAV GYAN CHAND</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_AP2011005946A03</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2011</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><toplevel>online_resources</toplevel><creatorcontrib>DORWAL HARISH N</creatorcontrib><creatorcontrib>TANWAR POOJA</creatorcontrib><creatorcontrib>YADAV GYAN CHAND</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>DORWAL HARISH N</au><au>TANWAR POOJA</au><au>YADAV GYAN CHAND</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>A process for the preparation of 1, 2, 4-trioxolane antimalarials</title><date>2011-10-31</date><risdate>2011</risdate><abstract>This invention relates to an improved process for the preparation of compounds of Formula I, salts of the free base cis-adamantane-2-spiro-3′-8′-[[[(2′-amino-2′-methylpropyl)amino]carbonyl]methyl]-1′,2′,4′-trioxaspiro[4.5]decane, Formula (I) wherein X is an anion. The compounds of Formula (I) have antimalarial activity.</abstract><oa>free_for_read</oa></addata></record>
fulltext	fulltext_linktorsrc
identifier
ispartof
issn
language	eng
recordid	cdi_epo_espacenet_AP2011005946A0
source	esp@cenet
subjects	CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY
title	A process for the preparation of 1, 2, 4-trioxolane antimalarials
url	https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-14T15%3A45%3A18IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=DORWAL%20HARISH%20N&rft.date=2011-10-31&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EAP2011005946A0%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true