KU-32, a Novel Drug for Diabetic Neuropathy, Is Safe for Human Islets and Improves In Vitro Insulin Secretion and Viability

KU-32 is a novel, novobiocin-based Hsp90 inhibitor that protects against neuronal glucotoxicity and reverses multiple clinical indices of diabetic peripheral neuropathy in a rodent model. However, any drug with potential for treating diabetic complications must also have no adverse effects on the fu...

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Veröffentlicht in:	Journal of diabetes research 2011, Vol.2012 (2012), p.1-11
Hauptverfasser:	Stehno-Bittel, Lisa, Blagg, Brian S. J., Rawal, Sonia, Ramachandran, Karthik, Novikova, Lesya, Williams, S. Janette, Farmer, Kevin, Dobrowsky, Rick
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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