Antioxidant, a-glucosidase inhibitory and anti-inflammatory effects of aerial parts extract from Korean crowberry (Empetrum nigrum var. japonicum)
Crowberry (Empetrum nigrum L.) is a wild berry commonly found in the northern hemisphere. Crowberry fruits have been suggested as good resources for functional applications in the cosmetic and pharmaceutical industries, but the high polyphenolic content in crowberry leaves also indicates crowberry a...
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| Veröffentlicht in: | Saudi journal of biological sciences 2016, Vol.23 (2), p.181-188 |
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| container_title | Saudi journal of biological sciences |
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| creator | Hyun, Tae Kyung Kim, Hyoun Chol Ko, Yeong Jong Kim, Ju Sung |
| description | Crowberry (Empetrum nigrum L.) is a wild berry commonly found in the northern
hemisphere. Crowberry fruits have been suggested as good resources for functional applications
in the cosmetic and pharmaceutical industries, but the high polyphenolic content in crowberry
leaves also indicates crowberry aerial parts as potential dietary health supplements. In this study,
therefore, the biological activities of the aerial parts of Korean crowberry (E. nigrum var.
japonicum) were investigated. Antioxidant activity was measured by three different assays on DPPH
free radical scavenging, reducing power, and total antioxidant capacities. Dose-dependent antioxidant
activities were exhibited by crude methanol extract and its fractions, suggesting that the crude
methanol extract and EtOAc fraction possessed strong antioxidant activities and capacities. In
addition, the crude methanol extract and EtOAc strongly inhibited a-glucosidase activity and suppressed
the secretion of pro-inflammatory mediator and nitrite oxide from LPS-stimulated RAW
264.7 cells. These findings provide valuable evidence for the potential of such parts as good dietary |
| format | Article |
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hemisphere. Crowberry fruits have been suggested as good resources for functional applications
in the cosmetic and pharmaceutical industries, but the high polyphenolic content in crowberry
leaves also indicates crowberry aerial parts as potential dietary health supplements. In this study,
therefore, the biological activities of the aerial parts of Korean crowberry (E. nigrum var.
japonicum) were investigated. Antioxidant activity was measured by three different assays on DPPH
free radical scavenging, reducing power, and total antioxidant capacities. Dose-dependent antioxidant
activities were exhibited by crude methanol extract and its fractions, suggesting that the crude
methanol extract and EtOAc fraction possessed strong antioxidant activities and capacities. In
addition, the crude methanol extract and EtOAc strongly inhibited a-glucosidase activity and suppressed
the secretion of pro-inflammatory mediator and nitrite oxide from LPS-stimulated RAW
264.7 cells. These findings provide valuable evidence for the potential of such parts as good dietary</description><identifier>ISSN: 1319-562X</identifier><language>eng</language><publisher>Riyadh, Saudi Arabia: Saudi Biological Society</publisher><ispartof>Saudi journal of biological sciences, 2016, Vol.23 (2), p.181-188</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780</link.rule.ids></links><search><creatorcontrib>Hyun, Tae Kyung</creatorcontrib><creatorcontrib>Kim, Hyoun Chol</creatorcontrib><creatorcontrib>Ko, Yeong Jong</creatorcontrib><creatorcontrib>Kim, Ju Sung</creatorcontrib><title>Antioxidant, a-glucosidase inhibitory and anti-inflammatory effects of aerial parts extract from Korean crowberry (Empetrum nigrum var. japonicum)</title><title>Saudi journal of biological sciences</title><description>Crowberry (Empetrum nigrum L.) is a wild berry commonly found in the northern
hemisphere. Crowberry fruits have been suggested as good resources for functional applications
in the cosmetic and pharmaceutical industries, but the high polyphenolic content in crowberry
leaves also indicates crowberry aerial parts as potential dietary health supplements. In this study,
therefore, the biological activities of the aerial parts of Korean crowberry (E. nigrum var.
japonicum) were investigated. Antioxidant activity was measured by three different assays on DPPH
free radical scavenging, reducing power, and total antioxidant capacities. Dose-dependent antioxidant
activities were exhibited by crude methanol extract and its fractions, suggesting that the crude
methanol extract and EtOAc fraction possessed strong antioxidant activities and capacities. In
addition, the crude methanol extract and EtOAc strongly inhibited a-glucosidase activity and suppressed
the secretion of pro-inflammatory mediator and nitrite oxide from LPS-stimulated RAW
264.7 cells. These findings provide valuable evidence for the potential of such parts as good dietary</description><issn>1319-562X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><recordid>eNqFi81qAkEQhOeg4E98BKGPBrLBzeqqxxAMglcPuUk79mjLzszSM-vPa-SJMxHvHoqqr4pqqW5e5ItsWn78dFQvhNN4XM6Led5Vv58usr_yHl18A8wOVaN9SBgI2B15x9HLDdDtkyJn7EyF1uK9JWNIxwDeAJIwVlCjJKZrFNQRjHgLay-EDrT4y44kvUZLW1OUxoLjw7-dUd7hhLV3rBv7-qLaBqtAg4f31fB7uflaZWRRyOC2Fk7pti1nk9liUjzb_wCdwlQM</recordid><startdate>2016</startdate><enddate>2016</enddate><creator>Hyun, Tae Kyung</creator><creator>Kim, Hyoun Chol</creator><creator>Ko, Yeong Jong</creator><creator>Kim, Ju Sung</creator><general>Saudi Biological Society</general><scope>ADJCN</scope><scope>AHFXO</scope></search><sort><creationdate>2016</creationdate><title>Antioxidant, a-glucosidase inhibitory and anti-inflammatory effects of aerial parts extract from Korean crowberry (Empetrum nigrum var. japonicum)</title><author>Hyun, Tae Kyung ; Kim, Hyoun Chol ; Ko, Yeong Jong ; Kim, Ju Sung</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-emarefa_primary_6747943</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hyun, Tae Kyung</creatorcontrib><creatorcontrib>Kim, Hyoun Chol</creatorcontrib><creatorcontrib>Ko, Yeong Jong</creatorcontrib><creatorcontrib>Kim, Ju Sung</creatorcontrib><collection>الدوريات العلمية والإحصائية - e-Marefa Academic and Statistical Periodicals</collection><collection>معرفة - المحتوى العربي الأكاديمي المتكامل - e-Marefa Academic Complete</collection><jtitle>Saudi journal of biological sciences</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hyun, Tae Kyung</au><au>Kim, Hyoun Chol</au><au>Ko, Yeong Jong</au><au>Kim, Ju Sung</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Antioxidant, a-glucosidase inhibitory and anti-inflammatory effects of aerial parts extract from Korean crowberry (Empetrum nigrum var. japonicum)</atitle><jtitle>Saudi journal of biological sciences</jtitle><date>2016</date><risdate>2016</risdate><volume>23</volume><issue>2</issue><spage>181</spage><epage>188</epage><pages>181-188</pages><issn>1319-562X</issn><abstract>Crowberry (Empetrum nigrum L.) is a wild berry commonly found in the northern
hemisphere. Crowberry fruits have been suggested as good resources for functional applications
in the cosmetic and pharmaceutical industries, but the high polyphenolic content in crowberry
leaves also indicates crowberry aerial parts as potential dietary health supplements. In this study,
therefore, the biological activities of the aerial parts of Korean crowberry (E. nigrum var.
japonicum) were investigated. Antioxidant activity was measured by three different assays on DPPH
free radical scavenging, reducing power, and total antioxidant capacities. Dose-dependent antioxidant
activities were exhibited by crude methanol extract and its fractions, suggesting that the crude
methanol extract and EtOAc fraction possessed strong antioxidant activities and capacities. In
addition, the crude methanol extract and EtOAc strongly inhibited a-glucosidase activity and suppressed
the secretion of pro-inflammatory mediator and nitrite oxide from LPS-stimulated RAW
264.7 cells. These findings provide valuable evidence for the potential of such parts as good dietary</abstract><cop>Riyadh, Saudi Arabia</cop><pub>Saudi Biological Society</pub><tpages>8</tpages></addata></record> |
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| source | Elsevier ScienceDirect Journals; EZB-FREE-00999 freely available EZB journals; PubMed Central |
| title | Antioxidant, a-glucosidase inhibitory and anti-inflammatory effects of aerial parts extract from Korean crowberry (Empetrum nigrum var. japonicum) |
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