Pinocembrin Protects Human Brain Microvascular Endothelial Cells against Fibrillar Amyloid- β1−40 Injury by Suppressing the MAPK/NF- κ B Inflammatory Pathways

Cerebrovascular accumulation of amyloid-β (Aβ) peptides in Alzheimer’s disease (AD) may contribute to disease progression through Aβ-induced microvascular endothelial pathogenesis. Pinocembrin has been shown to have therapeutic effects in AD models. These effects correlate with preservation of micro...

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Veröffentlicht in:	BioMed research international 2014, Vol.2014 (2014), p.1-14
Hauptverfasser:	Liu, Rui, Li, Jin-ze, Song, Jun-ke, Sun, Jia-lin, Li, Yong-jie, Zhou, Si-bai, Zhang, Tian-tai, Du, Guan-hua
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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